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- W2047060429 abstract "Paramyxoviruses evade antiviral immune response using a small nonstructural protein, V, which binds to the host dsRNA sensor MDA5 and prevents it from activating the interferon signaling pathway. A recent crystal structure of the V protein in complex with MDA5, published in Science, revealed that V disrupts the structure of MDA5 and is integrated into the MDA5 protein fold, providing an intriguing new example of viral mimicry as a countermeasure against the host immune system." @default.
- W2047060429 created "2016-06-24" @default.
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- W2047060429 date "2013-03-12" @default.
- W2047060429 modified "2023-10-10" @default.
- W2047060429 title "Viral counterattack against the host innate immune system" @default.
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- W2047060429 doi "https://doi.org/10.1038/cr.2013.32" @default.
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