Matches in SemOpenAlex for { <https://semopenalex.org/work/W2047116813> ?p ?o ?g. }
- W2047116813 endingPage "220" @default.
- W2047116813 startingPage "213" @default.
- W2047116813 abstract "To examine physical-chemical aspects of bile salt-phospholipid interactions that could contribute to preferential phosphatidylcholine (PC) secretion into bile, we have compared transitions between vesicles and micelles in model systems containing taurocholate (TC) and either egg-yolk PC (EYPC), egg-yolk sphingomyelin (EYSM), buttermilk SM (BMSM) or dipalmitoyl PC (DPPC). Phase transitions from micelles to vesicles were observed at 4-fold dilution of serially diluted EYPC/TC systems, but not earlier than at 16-fold dilution of SM/TC or DPPC/TC systems, indicating lower concentrations of the detergent required for micellization in the case of SM or DPPC. Cryo-transmission electron microscopy of phase transitions initiated by addition of TC to phospholipid vesicles revealed extremely long SM-containing intermediate structures, but shorter EYPC-containing intermediate structures. Again, larger amounts of bile salt were required to induce phase transitions in the case of EYPC compared to SM. Sizes of TC-phospholipid micelles increased progressively upon increasing phospholipid contents in the rank order: DPPC-TC<EYSM-TC<BMSM-TC<EYPC-TC, consistent with higher micellization concentrations in the case of EYPC. Micelles were also separated from vesicular phases in two-phase model systems composed with TC, both EYPC and EYSM and 0, 10, 20 or 30 mol% cholesterol, by ultracentrifugation and ultrafiltration of the supernatant. At increasing cholesterol contents, EYPC preferentially distributed into the micellar phase. In contrast, no preferential micellar EYPC distribution occurred in the absence of the sterol. These results indicate different structural arrangements of EYPC-TC micelles compared to SM-TC micelles and lower detergent concentrations required for micellization in the case of SM-containing vesicles." @default.
- W2047116813 created "2016-06-24" @default.
- W2047116813 creator A5010751448 @default.
- W2047116813 creator A5011340013 @default.
- W2047116813 creator A5015062996 @default.
- W2047116813 creator A5020023657 @default.
- W2047116813 creator A5045668995 @default.
- W2047116813 creator A5068809549 @default.
- W2047116813 date "2002-07-01" @default.
- W2047116813 modified "2023-09-27" @default.
- W2047116813 title "Different interactions of egg-yolk phosphatidylcholine and sphingomyelin with detergent bile salts" @default.
- W2047116813 cites W1508525237 @default.
- W2047116813 cites W1595123479 @default.
- W2047116813 cites W1753148847 @default.
- W2047116813 cites W1858850028 @default.
- W2047116813 cites W1963904764 @default.
- W2047116813 cites W1967114224 @default.
- W2047116813 cites W1971091498 @default.
- W2047116813 cites W1974138502 @default.
- W2047116813 cites W1974928798 @default.
- W2047116813 cites W1975821967 @default.
- W2047116813 cites W1982071945 @default.
- W2047116813 cites W1986988975 @default.
- W2047116813 cites W2003709444 @default.
- W2047116813 cites W2007879482 @default.
- W2047116813 cites W2013912675 @default.
- W2047116813 cites W2020700452 @default.
- W2047116813 cites W2021559754 @default.
- W2047116813 cites W2027127398 @default.
- W2047116813 cites W2031909431 @default.
- W2047116813 cites W2032350462 @default.
- W2047116813 cites W2037735248 @default.
- W2047116813 cites W2043906991 @default.
- W2047116813 cites W2046875885 @default.
- W2047116813 cites W2057901960 @default.
- W2047116813 cites W2061569374 @default.
- W2047116813 cites W2064601385 @default.
- W2047116813 cites W2065751076 @default.
- W2047116813 cites W2069568296 @default.
- W2047116813 cites W2087688721 @default.
- W2047116813 cites W2091084349 @default.
- W2047116813 cites W2098151972 @default.
- W2047116813 cites W2128559420 @default.
- W2047116813 cites W2129215604 @default.
- W2047116813 cites W2141061210 @default.
- W2047116813 cites W2152438501 @default.
- W2047116813 cites W2152972067 @default.
- W2047116813 cites W2168526937 @default.
- W2047116813 cites W2172134989 @default.
- W2047116813 cites W2181362394 @default.
- W2047116813 cites W2315027299 @default.
- W2047116813 cites W2340031902 @default.
- W2047116813 cites W2342768389 @default.
- W2047116813 cites W2384576388 @default.
- W2047116813 cites W4323285295 @default.
- W2047116813 doi "https://doi.org/10.1016/s1388-1981(02)00215-9" @default.
- W2047116813 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12117565" @default.
- W2047116813 hasPublicationYear "2002" @default.
- W2047116813 type Work @default.
- W2047116813 sameAs 2047116813 @default.
- W2047116813 citedByCount "5" @default.
- W2047116813 countsByYear W20471168132013 @default.
- W2047116813 countsByYear W20471168132019 @default.
- W2047116813 countsByYear W20471168132021 @default.
- W2047116813 crossrefType "journal-article" @default.
- W2047116813 hasAuthorship W2047116813A5010751448 @default.
- W2047116813 hasAuthorship W2047116813A5011340013 @default.
- W2047116813 hasAuthorship W2047116813A5015062996 @default.
- W2047116813 hasAuthorship W2047116813A5020023657 @default.
- W2047116813 hasAuthorship W2047116813A5045668995 @default.
- W2047116813 hasAuthorship W2047116813A5068809549 @default.
- W2047116813 hasConcept C11268172 @default.
- W2047116813 hasConcept C121332964 @default.
- W2047116813 hasConcept C130316041 @default.
- W2047116813 hasConcept C178790620 @default.
- W2047116813 hasConcept C184651966 @default.
- W2047116813 hasConcept C185592680 @default.
- W2047116813 hasConcept C2776330855 @default.
- W2047116813 hasConcept C2778918659 @default.
- W2047116813 hasConcept C41625074 @default.
- W2047116813 hasConcept C43617362 @default.
- W2047116813 hasConcept C55493867 @default.
- W2047116813 hasConcept C61322309 @default.
- W2047116813 hasConcept C8010536 @default.
- W2047116813 hasConcept C96618451 @default.
- W2047116813 hasConcept C97355855 @default.
- W2047116813 hasConceptScore W2047116813C11268172 @default.
- W2047116813 hasConceptScore W2047116813C121332964 @default.
- W2047116813 hasConceptScore W2047116813C130316041 @default.
- W2047116813 hasConceptScore W2047116813C178790620 @default.
- W2047116813 hasConceptScore W2047116813C184651966 @default.
- W2047116813 hasConceptScore W2047116813C185592680 @default.
- W2047116813 hasConceptScore W2047116813C2776330855 @default.
- W2047116813 hasConceptScore W2047116813C2778918659 @default.
- W2047116813 hasConceptScore W2047116813C41625074 @default.
- W2047116813 hasConceptScore W2047116813C43617362 @default.
- W2047116813 hasConceptScore W2047116813C55493867 @default.
- W2047116813 hasConceptScore W2047116813C61322309 @default.