FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2047250419> ?p ?o ?g. }

• W2047250419 abstract "A study of anionic sites in the glomerular basement membrane (GBM) from patients with immunoglobulin A (IgA) nephropathy is described. The relationship between the deposition of IgA and the detection of glomerular extracellular components, i.e., noncollagenous (NC-1) domain of Type IV collagen, in the glomerular capillary walls was examined by double immunofluorescence. Renal biopsy specimens from patients with IgA nephropathy were immersed in polyethyleneimine (PEI) as a cationic probe and then examined by electron microscopy. Renal specimens were also incubated with mouse monoclonal anti-NC-1 domain of Type IV collagen and then stained with fluorescein isothiocyanate (FITC)-labelled goat antimouse Ig antiserum. After these reactions, sections were stained with rhodamine-labelled rabbit antihuman IgA antiserum. GBM subepithelial anionic sites marked by PEI were altered by the deposition of electron-dense deposits (EDD) in patients with IgA nephropathy and there was a significant correlation between the levels of proteinuria and the incidence of EDD in the GBM in such patients. Marked proteinuria was observed in patients who showed loss of anionic sites in the GBM by electron microscopy. By double immunofluorescence, IgA was shown to be focally deposited outside the NC-1 domain of Type IV collagen-detected regions in the same patients. The authors concluded that high levels of proteinuria might be due to alterations of the size barrier and/or anionic sites of GBM in the moderate stage of IgA nephropathy." @default.
• W2047250419 created "2016-06-24" @default.
• W2047250419 creator A5006762904 @default.
• W2047250419 creator A5024088462 @default.
• W2047250419 creator A5029801091 @default.
• W2047250419 creator A5033719766 @default.
• W2047250419 creator A5053648823 @default.
• W2047250419 creator A5068472311 @default.
• W2047250419 creator A5078494019 @default.
• W2047250419 creator A5083142818 @default.
• W2047250419 date "1989-01-01" @default.
• W2047250419 modified "2023-10-13" @default.
• W2047250419 title "Detection of anionic sites and immunoglobulin a deposits in the glomerular capillary walls from patients with Iga nephropathy" @default.
• W2047250419 cites W1486875089 @default.
• W2047250419 cites W1986971521 @default.
• W2047250419 cites W1997876838 @default.
• W2047250419 cites W2023942776 @default.
• W2047250419 cites W2026679472 @default.
• W2047250419 cites W2027161422 @default.
• W2047250419 cites W2049939760 @default.
• W2047250419 cites W2215002812 @default.
• W2047250419 doi "https://doi.org/10.1002/jcla.1860030207" @default.
• W2047250419 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2659755" @default.
• W2047250419 hasPublicationYear "1989" @default.
• W2047250419 type Work @default.
• W2047250419 sameAs 2047250419 @default.
• W2047250419 citedByCount "10" @default.
• W2047250419 countsByYear W20472504192017 @default.
• W2047250419 crossrefType "journal-article" @default.
• W2047250419 hasAuthorship W2047250419A5006762904 @default.
• W2047250419 hasAuthorship W2047250419A5024088462 @default.
• W2047250419 hasAuthorship W2047250419A5029801091 @default.
• W2047250419 hasAuthorship W2047250419A5033719766 @default.
• W2047250419 hasAuthorship W2047250419A5053648823 @default.
• W2047250419 hasAuthorship W2047250419A5068472311 @default.
• W2047250419 hasAuthorship W2047250419A5078494019 @default.
• W2047250419 hasAuthorship W2047250419A5083142818 @default.
• W2047250419 hasConcept C121332964 @default.
• W2047250419 hasConcept C126322002 @default.
• W2047250419 hasConcept C134018914 @default.
• W2047250419 hasConcept C142724271 @default.
• W2047250419 hasConcept C153911025 @default.
• W2047250419 hasConcept C159654299 @default.
• W2047250419 hasConcept C185592680 @default.
• W2047250419 hasConcept C189165786 @default.
• W2047250419 hasConcept C203014093 @default.
• W2047250419 hasConcept C2775934546 @default.
• W2047250419 hasConcept C2776115139 @default.
• W2047250419 hasConcept C2776193487 @default.
• W2047250419 hasConcept C2777019933 @default.
• W2047250419 hasConcept C2777107211 @default.
• W2047250419 hasConcept C2778015030 @default.
• W2047250419 hasConcept C2778236600 @default.
• W2047250419 hasConcept C2779102806 @default.
• W2047250419 hasConcept C2779561371 @default.
• W2047250419 hasConcept C2779814568 @default.
• W2047250419 hasConcept C2780091579 @default.
• W2047250419 hasConcept C2780368995 @default.
• W2047250419 hasConcept C2780898057 @default.
• W2047250419 hasConcept C2781087799 @default.
• W2047250419 hasConcept C2781184683 @default.
• W2047250419 hasConcept C2910125355 @default.
• W2047250419 hasConcept C3018920779 @default.
• W2047250419 hasConcept C55493867 @default.
• W2047250419 hasConcept C555293320 @default.
• W2047250419 hasConcept C62520636 @default.
• W2047250419 hasConcept C71924100 @default.
• W2047250419 hasConcept C86803240 @default.
• W2047250419 hasConcept C91523082 @default.
• W2047250419 hasConcept C91881484 @default.
• W2047250419 hasConceptScore W2047250419C121332964 @default.
• W2047250419 hasConceptScore W2047250419C126322002 @default.
• W2047250419 hasConceptScore W2047250419C134018914 @default.
• W2047250419 hasConceptScore W2047250419C142724271 @default.
• W2047250419 hasConceptScore W2047250419C153911025 @default.
• W2047250419 hasConceptScore W2047250419C159654299 @default.
• W2047250419 hasConceptScore W2047250419C185592680 @default.
• W2047250419 hasConceptScore W2047250419C189165786 @default.
• W2047250419 hasConceptScore W2047250419C203014093 @default.
• W2047250419 hasConceptScore W2047250419C2775934546 @default.
• W2047250419 hasConceptScore W2047250419C2776115139 @default.
• W2047250419 hasConceptScore W2047250419C2776193487 @default.
• W2047250419 hasConceptScore W2047250419C2777019933 @default.
• W2047250419 hasConceptScore W2047250419C2777107211 @default.
• W2047250419 hasConceptScore W2047250419C2778015030 @default.
• W2047250419 hasConceptScore W2047250419C2778236600 @default.
• W2047250419 hasConceptScore W2047250419C2779102806 @default.
• W2047250419 hasConceptScore W2047250419C2779561371 @default.
• W2047250419 hasConceptScore W2047250419C2779814568 @default.
• W2047250419 hasConceptScore W2047250419C2780091579 @default.
• W2047250419 hasConceptScore W2047250419C2780368995 @default.
• W2047250419 hasConceptScore W2047250419C2780898057 @default.
• W2047250419 hasConceptScore W2047250419C2781087799 @default.
• W2047250419 hasConceptScore W2047250419C2781184683 @default.
• W2047250419 hasConceptScore W2047250419C2910125355 @default.
• W2047250419 hasConceptScore W2047250419C3018920779 @default.
• W2047250419 hasConceptScore W2047250419C55493867 @default.
• W2047250419 hasConceptScore W2047250419C555293320 @default.
• W2047250419 hasConceptScore W2047250419C62520636 @default.
• W2047250419 hasConceptScore W2047250419C71924100 @default.

• next