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• W2047351570 abstract "AL-amyloidoses are generally described as a group of disorders in which N-terminal fragments of monoclonal immunoglobulin light chains are transferred into amyloid fibrils. We have, by amino acid sequence analyses and immunological methods, characterized the Bence-Jones protein and the corresponding AL protein as a kappa III immunoglobulin light chain from material of a patient with systemic AL-amyloidosis presenting as a local inguinal tumour. The two proteins showed some unique features. The major part of the AL amyloid fibril protein consisted of C-terminal fragments of the Bence-Jones protein. Furthermore, both the Bence-Jones protein and the AL protein were glycosylated, with possibly a glycosylation in the constant part of the light chain." @default.
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• W2047351570 date "1998-07-01" @default.
• W2047351570 modified "2023-09-26" @default.
• W2047351570 title "Constant Region of a κ III Immunoglobulin Light Chain as a Major AL‐Amyloid Protein" @default.
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• W2047351570 doi "https://doi.org/10.1046/j.1365-3083.1998.00352.x" @default.
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