Matches in SemOpenAlex for { <https://semopenalex.org/work/W2047360972> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2047360972 endingPage "1419" @default.
- W2047360972 startingPage "1416" @default.
- W2047360972 abstract "α-Amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD) plays a key role in the regulation of NAD biosynthesis or the production of quinolinate from tryptophan (Trp). We investigated in this study the effect of phytol, a phytochemical known as a peroxisome proliferator-activated receptor α (PPARα) ligand, on NAD synthesis and ACMSD expression in rats. Male Sprague-Dawley rats were fed a diet containing 0.5%, 1%, or 2% phytol for 7 d. Phytol decreased the ACMSD activity and its mRNA expression in a dose-dependent manner in the liver. Phytol similarly and significantly suppressed ACMSD mRNA expression in primary rat hepatocytes. However, the mRNA expression of ACO (a known PPARα target gene) was higher in the low-phytol groups than in the high-phytol group in vivo and in vitro. Phytol increased the blood NAD level by suppressing ACMSD mRNA expression in the liver of the rats. It is possible that this mechanism occurred by the activation of PPARα and also of other transcriptional factors." @default.
- W2047360972 created "2016-06-24" @default.
- W2047360972 creator A5010450102 @default.
- W2047360972 creator A5034376226 @default.
- W2047360972 creator A5077553882 @default.
- W2047360972 creator A5078577516 @default.
- W2047360972 date "2013-07-23" @default.
- W2047360972 modified "2023-10-10" @default.
- W2047360972 title "Effect of Dietary Phytol on the Expression of α-Amino-β-carboxymuconate-ε-semialdehyde Decarboxylase, a Key Enzyme of Tryptophan-niacin Metabolism, in Rats" @default.
- W2047360972 cites W184980440 @default.
- W2047360972 cites W1914294451 @default.
- W2047360972 cites W1974161676 @default.
- W2047360972 cites W1975901487 @default.
- W2047360972 cites W1977122892 @default.
- W2047360972 cites W1979072266 @default.
- W2047360972 cites W1986136826 @default.
- W2047360972 cites W2004214261 @default.
- W2047360972 cites W2013419345 @default.
- W2047360972 cites W2019240387 @default.
- W2047360972 cites W2045394065 @default.
- W2047360972 cites W2046146399 @default.
- W2047360972 cites W2046746216 @default.
- W2047360972 cites W2053124968 @default.
- W2047360972 cites W2064178372 @default.
- W2047360972 cites W2068196407 @default.
- W2047360972 cites W2077605590 @default.
- W2047360972 cites W2099356672 @default.
- W2047360972 cites W2099966822 @default.
- W2047360972 cites W2117270297 @default.
- W2047360972 cites W2119365541 @default.
- W2047360972 cites W2145791380 @default.
- W2047360972 cites W2150557496 @default.
- W2047360972 cites W2159242199 @default.
- W2047360972 cites W2183416404 @default.
- W2047360972 cites W3105189695 @default.
- W2047360972 doi "https://doi.org/10.1271/bbb.130029" @default.
- W2047360972 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23832361" @default.
- W2047360972 hasPublicationYear "2013" @default.
- W2047360972 type Work @default.
- W2047360972 sameAs 2047360972 @default.
- W2047360972 citedByCount "5" @default.
- W2047360972 countsByYear W20473609722017 @default.
- W2047360972 countsByYear W20473609722018 @default.
- W2047360972 countsByYear W20473609722022 @default.
- W2047360972 crossrefType "journal-article" @default.
- W2047360972 hasAuthorship W2047360972A5010450102 @default.
- W2047360972 hasAuthorship W2047360972A5034376226 @default.
- W2047360972 hasAuthorship W2047360972A5077553882 @default.
- W2047360972 hasAuthorship W2047360972A5078577516 @default.
- W2047360972 hasBestOaLocation W20473609721 @default.
- W2047360972 hasConcept C181199279 @default.
- W2047360972 hasConcept C2776593056 @default.
- W2047360972 hasConcept C2776706248 @default.
- W2047360972 hasConcept C2777896816 @default.
- W2047360972 hasConcept C2780092750 @default.
- W2047360972 hasConcept C2910635417 @default.
- W2047360972 hasConcept C515207424 @default.
- W2047360972 hasConcept C55493867 @default.
- W2047360972 hasConcept C75520062 @default.
- W2047360972 hasConcept C86803240 @default.
- W2047360972 hasConceptScore W2047360972C181199279 @default.
- W2047360972 hasConceptScore W2047360972C2776593056 @default.
- W2047360972 hasConceptScore W2047360972C2776706248 @default.
- W2047360972 hasConceptScore W2047360972C2777896816 @default.
- W2047360972 hasConceptScore W2047360972C2780092750 @default.
- W2047360972 hasConceptScore W2047360972C2910635417 @default.
- W2047360972 hasConceptScore W2047360972C515207424 @default.
- W2047360972 hasConceptScore W2047360972C55493867 @default.
- W2047360972 hasConceptScore W2047360972C75520062 @default.
- W2047360972 hasConceptScore W2047360972C86803240 @default.
- W2047360972 hasIssue "7" @default.
- W2047360972 hasLocation W20473609721 @default.
- W2047360972 hasLocation W20473609722 @default.
- W2047360972 hasOpenAccess W2047360972 @default.
- W2047360972 hasPrimaryLocation W20473609721 @default.
- W2047360972 hasRelatedWork W1872723650 @default.
- W2047360972 hasRelatedWork W1907486870 @default.
- W2047360972 hasRelatedWork W1984899437 @default.
- W2047360972 hasRelatedWork W1989934810 @default.
- W2047360972 hasRelatedWork W2018015697 @default.
- W2047360972 hasRelatedWork W2034385163 @default.
- W2047360972 hasRelatedWork W2159116562 @default.
- W2047360972 hasRelatedWork W2162127748 @default.
- W2047360972 hasRelatedWork W2887579551 @default.
- W2047360972 hasRelatedWork W67428074 @default.
- W2047360972 hasVolume "77" @default.
- W2047360972 isParatext "false" @default.
- W2047360972 isRetracted "false" @default.
- W2047360972 magId "2047360972" @default.
- W2047360972 workType "article" @default.