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- W2047390709 abstract "53歳,女性.10年間の維持透析歴あり.偶然,高レニン・高アルドステロン血症を指摘され入院.血漿アルドステロン濃度は40,080pg/mLと著明高値を認めた.右副腎腫瘍を認め各種内分泌的検査結果より,腎細動脈硬化によるレニン上昇とアルドステロン産生副腎腺腫による原発性アルドステロン症の合併と診断した.右副腎摘除術施行.術後,血漿アルドステロン濃度は低下した.慢性腎不全患者においては,時に著明な高アルドステロン血症を呈する例が散見される.腎不全の病態においては,各種のアルドステロン分泌抑制因子が減弱することから適切なネガティブフィードバック機構が作用せず,より高値をとりやすいと考えた.また維持透析患者ではアルドステロン測定系に干渉する物質が存在すると思われ,その評価は慎重に行う必要がある." @default.
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- W2047390709 title "Primary aldosteronism due to aldosterone-producing adrenocortical adenoma with high plasma renin activity and massive elevation of plasma aldosterone concentration in a maintained hemodialysis patient" @default.
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