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- W2047402016 abstract "Therapeutic doses of indomethacin, aspirin, and ibuprofen were administered to New Zealand White rabbits after implantation of a porouscoated chrome--cobalt implant. Quantitative his-tomorphometric analysis was used to calculate the amount of bone occupying the pores. There was a statistically significant decrease in bone ingrowth in animals treated with indomethacin, ibuprofen, and high-dose aspirin when compared to a control group. There was a dose-response effect for the indomethacin and aspirin groups, with higher doses having a greater inhibitory effect. Indomethacin, ibuprofen, and high-dose aspirin may be contraindicated during the immediate postoperative period in patients having cementless arthro-plasty." @default.
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- W2047402016 date "1989-12-01" @default.
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- W2047402016 title "The Effect of Indomethacin, Aspirin, and Ibuprofen on Bone Ingrowth Into a Porous-Coated Implant" @default.
- W2047402016 doi "https://doi.org/10.1097/00003086-198912000-00013" @default.
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