FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2047449436> ?p ?o ?g. }

• W2047449436 endingPage "266" @default.
• W2047449436 startingPage "261" @default.
• W2047449436 abstract "Objective As not all patients with similar risk factors and eliciting conditions develop delirium; it may be hypothesized that genetic variation may play a role in the risk of delirium. On the basis of the relationship between dementia, respectively reduced cholinergic activity, and the APOE ε4-allele, and the similarities between dementia and delirium in reduced cholinergic activity, the APOE ε4-allele is a rational candidate-gene for delirium. This study examined the association between APOE ε4-allele and delirium in elderly patients. Methods Acutely admitted patients to the Department of Medicine of 65 years and over were included during a 27-month time period. Delirium was scored by the confusion assessment method. Cognitive impairment was diagnosed by Mini Mental State Examination and informant questionnaire on cognitive decline. Genotyping was done with matrix-assisted laser-desorption/ionization time-of flight mass spectrometry. Results Of 415 included patients, a random sample of 264 patients was genotyped for APOE. The patients who met the criteria for delirium (35%) were significantly older and more frequently had preexisting functional and cognitive impairment. APOE genotype was borderline significantly associated with cognitive impairment in patients below 75 years (P=0.057). The odds ratio for carriers of an APOE ε4-allele compared with patients without an APOE ε4-allele for developing delirium was 1.17 (95% confidence interval (CI): 0.49–2.78) in the cognitively intact patients and 0.42 (95% CI: 0.14–1.30) in the cognitively impaired patients. No relation existed between the total number of APOE ε4-alleles and the different delirium subtypes (P=0.12). Conclusions We found no convincing evidence that carriers of the APOE ε4-allele have a higher risk of delirium." @default.
• W2047449436 created "2016-06-24" @default.
• W2047449436 creator A5024730616 @default.
• W2047449436 creator A5038678186 @default.
• W2047449436 creator A5051056050 @default.
• W2047449436 creator A5055689793 @default.
• W2047449436 creator A5080723184 @default.
• W2047449436 date "2007-10-01" @default.
• W2047449436 modified "2023-10-18" @default.
• W2047449436 title "The association between delirium and the apolipoprotein E ε4 allele in the elderly" @default.
• W2047449436 cites W1564138526 @default.
• W2047449436 cites W1701089706 @default.
• W2047449436 cites W1847168837 @default.
• W2047449436 cites W1961904860 @default.
• W2047449436 cites W1968892572 @default.
• W2047449436 cites W1968996734 @default.
• W2047449436 cites W1969314235 @default.
• W2047449436 cites W1971990805 @default.
• W2047449436 cites W1979460577 @default.
• W2047449436 cites W1980501956 @default.
• W2047449436 cites W1984737558 @default.
• W2047449436 cites W1989113938 @default.
• W2047449436 cites W2000445173 @default.
• W2047449436 cites W2006437426 @default.
• W2047449436 cites W2011899776 @default.
• W2047449436 cites W2012355806 @default.
• W2047449436 cites W2015775451 @default.
• W2047449436 cites W2036985020 @default.
• W2047449436 cites W2037615335 @default.
• W2047449436 cites W2050140838 @default.
• W2047449436 cites W2059156466 @default.
• W2047449436 cites W2061879864 @default.
• W2047449436 cites W2062038040 @default.
• W2047449436 cites W2081033553 @default.
• W2047449436 cites W2082357989 @default.
• W2047449436 cites W2097142000 @default.
• W2047449436 cites W2122196056 @default.
• W2047449436 cites W2123627479 @default.
• W2047449436 cites W2132563603 @default.
• W2047449436 cites W2140455646 @default.
• W2047449436 cites W2146842791 @default.
• W2047449436 cites W2150841915 @default.
• W2047449436 cites W2170141710 @default.
• W2047449436 doi "https://doi.org/10.1097/ypg.0b013e3280c8efd4" @default.
• W2047449436 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17728664" @default.
• W2047449436 hasPublicationYear "2007" @default.
• W2047449436 type Work @default.
• W2047449436 sameAs 2047449436 @default.
• W2047449436 citedByCount "38" @default.
• W2047449436 countsByYear W20474494362012 @default.
• W2047449436 countsByYear W20474494362013 @default.
• W2047449436 countsByYear W20474494362014 @default.
• W2047449436 countsByYear W20474494362015 @default.
• W2047449436 countsByYear W20474494362016 @default.
• W2047449436 countsByYear W20474494362017 @default.
• W2047449436 countsByYear W20474494362018 @default.
• W2047449436 countsByYear W20474494362020 @default.
• W2047449436 crossrefType "journal-article" @default.
• W2047449436 hasAuthorship W2047449436A5024730616 @default.
• W2047449436 hasAuthorship W2047449436A5038678186 @default.
• W2047449436 hasAuthorship W2047449436A5051056050 @default.
• W2047449436 hasAuthorship W2047449436A5055689793 @default.
• W2047449436 hasAuthorship W2047449436A5080723184 @default.
• W2047449436 hasConcept C104317684 @default.
• W2047449436 hasConcept C118552586 @default.
• W2047449436 hasConcept C126322002 @default.
• W2047449436 hasConcept C156957248 @default.
• W2047449436 hasConcept C15744967 @default.
• W2047449436 hasConcept C180754005 @default.
• W2047449436 hasConcept C2779134260 @default.
• W2047449436 hasConcept C2779483572 @default.
• W2047449436 hasConcept C2779753318 @default.
• W2047449436 hasConcept C44249647 @default.
• W2047449436 hasConcept C54355233 @default.
• W2047449436 hasConcept C57089818 @default.
• W2047449436 hasConcept C71924100 @default.
• W2047449436 hasConcept C86803240 @default.
• W2047449436 hasConceptScore W2047449436C104317684 @default.
• W2047449436 hasConceptScore W2047449436C118552586 @default.
• W2047449436 hasConceptScore W2047449436C126322002 @default.
• W2047449436 hasConceptScore W2047449436C156957248 @default.
• W2047449436 hasConceptScore W2047449436C15744967 @default.
• W2047449436 hasConceptScore W2047449436C180754005 @default.
• W2047449436 hasConceptScore W2047449436C2779134260 @default.
• W2047449436 hasConceptScore W2047449436C2779483572 @default.
• W2047449436 hasConceptScore W2047449436C2779753318 @default.
• W2047449436 hasConceptScore W2047449436C44249647 @default.
• W2047449436 hasConceptScore W2047449436C54355233 @default.
• W2047449436 hasConceptScore W2047449436C57089818 @default.
• W2047449436 hasConceptScore W2047449436C71924100 @default.
• W2047449436 hasConceptScore W2047449436C86803240 @default.
• W2047449436 hasIssue "5" @default.
• W2047449436 hasLocation W20474494361 @default.
• W2047449436 hasLocation W20474494362 @default.
• W2047449436 hasOpenAccess W2047449436 @default.
• W2047449436 hasPrimaryLocation W20474494361 @default.
• W2047449436 hasRelatedWork W1532171259 @default.
• W2047449436 hasRelatedWork W2027372970 @default.

• next