FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2047492747> ?p ?o ?g. }

• W2047492747 endingPage "1710" @default.
• W2047492747 startingPage "1707" @default.
• W2047492747 abstract "To investigate the long-term biological effect of extreme low dose ionising radiation, we irradiated normal human fibroblasts (HFLIII) with carbon ions (290 MeV u−1, 70 keV μm−1) and γ-rays at 1 mGy (total dose) once at a low dose rate (1 mGy 6–8 h−1), and observed the cell growth kinetics up to 5 months by continuous culturing. The growth of carbon-irradiated cells started to slow down considerably sooner than that of non-irradiated cells before reaching senescence. In contrast, cells irradiated with γ-rays under similar conditions did not show significant deviation from the non-irradiated cells. A DNA double strand break (DSB) marker, γ-H2AX foci, and a DSB repair marker, phosphorylated DNA-PKcs foci, increased in number when non-irradiated cells reached several passages before senescence. A single low dose/low dose rate carbon ion exposure further raised the numbers of these markers. Furthermore, the numbers of foci for these two markers were significantly reduced after the cells became fully senescent. Our results indicate that high linear energy transfer (LET) radiation (carbon ions) causes different effects than low LET radiation (γ-rays) even at very low doses and that a single low dose of heavy ion irradiation can affect the stability of the genome many generations after irradiation." @default.
• W2047492747 created "2016-06-24" @default.
• W2047492747 creator A5001426072 @default.
• W2047492747 creator A5001743219 @default.
• W2047492747 creator A5006229702 @default.
• W2047492747 creator A5008712114 @default.
• W2047492747 creator A5012039871 @default.
• W2047492747 creator A5014082770 @default.
• W2047492747 creator A5058623548 @default.
• W2047492747 creator A5067969247 @default.
• W2047492747 date "2007-05-08" @default.
• W2047492747 modified "2023-10-09" @default.
• W2047492747 title "Single extreme low dose/low dose rate irradiation causes alteration in lifespan and genome instability in primary human cells" @default.
• W2047492747 cites W1517051009 @default.
• W2047492747 cites W1969334411 @default.
• W2047492747 cites W1970891016 @default.
• W2047492747 cites W1972655555 @default.
• W2047492747 cites W1976467983 @default.
• W2047492747 cites W2004314923 @default.
• W2047492747 cites W2019219567 @default.
• W2047492747 cites W2019405732 @default.
• W2047492747 cites W2020717634 @default.
• W2047492747 cites W2024004426 @default.
• W2047492747 cites W2024068850 @default.
• W2047492747 cites W2027931017 @default.
• W2047492747 cites W2041198010 @default.
• W2047492747 cites W2066033386 @default.
• W2047492747 cites W2069625482 @default.
• W2047492747 cites W2078281194 @default.
• W2047492747 cites W2109369265 @default.
• W2047492747 cites W2110177038 @default.
• W2047492747 cites W2162977273 @default.
• W2047492747 cites W2166284889 @default.
• W2047492747 cites W2168123285 @default.
• W2047492747 cites W2169009248 @default.
• W2047492747 doi "https://doi.org/10.1038/sj.bjc.6603775" @default.
• W2047492747 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2359922" @default.
• W2047492747 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17486133" @default.
• W2047492747 hasPublicationYear "2007" @default.
• W2047492747 type Work @default.
• W2047492747 sameAs 2047492747 @default.
• W2047492747 citedByCount "26" @default.
• W2047492747 countsByYear W20474927472012 @default.
• W2047492747 countsByYear W20474927472013 @default.
• W2047492747 countsByYear W20474927472015 @default.
• W2047492747 countsByYear W20474927472016 @default.
• W2047492747 countsByYear W20474927472017 @default.
• W2047492747 countsByYear W20474927472018 @default.
• W2047492747 countsByYear W20474927472020 @default.
• W2047492747 countsByYear W20474927472021 @default.
• W2047492747 crossrefType "journal-article" @default.
• W2047492747 hasAuthorship W2047492747A5001426072 @default.
• W2047492747 hasAuthorship W2047492747A5001743219 @default.
• W2047492747 hasAuthorship W2047492747A5006229702 @default.
• W2047492747 hasAuthorship W2047492747A5008712114 @default.
• W2047492747 hasAuthorship W2047492747A5012039871 @default.
• W2047492747 hasAuthorship W2047492747A5014082770 @default.
• W2047492747 hasAuthorship W2047492747A5058623548 @default.
• W2047492747 hasAuthorship W2047492747A5067969247 @default.
• W2047492747 hasBestOaLocation W20474927471 @default.
• W2047492747 hasConcept C111337013 @default.
• W2047492747 hasConcept C11928243 @default.
• W2047492747 hasConcept C121332964 @default.
• W2047492747 hasConcept C12554922 @default.
• W2047492747 hasConcept C134018914 @default.
• W2047492747 hasConcept C143425029 @default.
• W2047492747 hasConcept C1491633281 @default.
• W2047492747 hasConcept C153911025 @default.
• W2047492747 hasConcept C178169997 @default.
• W2047492747 hasConcept C18231593 @default.
• W2047492747 hasConcept C185544564 @default.
• W2047492747 hasConcept C2910144714 @default.
• W2047492747 hasConcept C522857546 @default.
• W2047492747 hasConcept C54355233 @default.
• W2047492747 hasConcept C552990157 @default.
• W2047492747 hasConcept C79410662 @default.
• W2047492747 hasConcept C86611320 @default.
• W2047492747 hasConcept C86803240 @default.
• W2047492747 hasConcept C95444343 @default.
• W2047492747 hasConceptScore W2047492747C111337013 @default.
• W2047492747 hasConceptScore W2047492747C11928243 @default.
• W2047492747 hasConceptScore W2047492747C121332964 @default.
• W2047492747 hasConceptScore W2047492747C12554922 @default.
• W2047492747 hasConceptScore W2047492747C134018914 @default.
• W2047492747 hasConceptScore W2047492747C143425029 @default.
• W2047492747 hasConceptScore W2047492747C1491633281 @default.
• W2047492747 hasConceptScore W2047492747C153911025 @default.
• W2047492747 hasConceptScore W2047492747C178169997 @default.
• W2047492747 hasConceptScore W2047492747C18231593 @default.
• W2047492747 hasConceptScore W2047492747C185544564 @default.
• W2047492747 hasConceptScore W2047492747C2910144714 @default.
• W2047492747 hasConceptScore W2047492747C522857546 @default.
• W2047492747 hasConceptScore W2047492747C54355233 @default.
• W2047492747 hasConceptScore W2047492747C552990157 @default.
• W2047492747 hasConceptScore W2047492747C79410662 @default.
• W2047492747 hasConceptScore W2047492747C86611320 @default.
• W2047492747 hasConceptScore W2047492747C86803240 @default.
• W2047492747 hasConceptScore W2047492747C95444343 @default.

• next