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- W2047511537 abstract "Sodium acetylsalicylate (100 mg/kg) intravenously injected into anaesthetized intact or decapitate cats caused an increase in body temperature. At a dosage of 30 mg per kilogram it caused a lowering of body temperature in the intact preparations, but again an increase in decapitate preparations. At a dosage of 10 mg per kilogram, no significant temperature change occurred in either type of preparation. Aspirin (in the form of sodium acetylsalicylate) is a systemic pyrogen and a centrally acting antipyretic. When it occurs, aspirin antipyresis must take place in the face of systemic pyrogenesis. Notable is the fact that aspirin (30 mg/kg) in the intact preparation lowers body temperature not only from fever levels, but also from normal and subnormal levels." @default.
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- W2047511537 date "1969-12-01" @default.
- W2047511537 modified "2023-10-16" @default.
- W2047511537 title "HYPERPYREXIA AND ANTIPYRESIS OWING TO SODIUM ACETYLSALICYLATE IN INTACT AND DECAPITATE CATS" @default.
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- W2047511537 doi "https://doi.org/10.1073/pnas.64.4.1165" @default.
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