Matches in SemOpenAlex for { <https://semopenalex.org/work/W2047546501> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W2047546501 abstract "An optical detector suitable for inclusion in tomographic arrangements for non-contact in vivo bioluminescence and fluorescence imaging applications is proposed. It consists of a microlens array (MLA) intended for field-of-view definition, a large-field complementary metal-oxide-semiconductor (CMOS) chip for light detection, a septum mask for cross-talk suppression, and an exchangeable filter to block excitation light. Prototype detector units with sensitive areas of 2.5 cm x 5 cm each were assembled. The CMOS sensor constitutes a 512 x 1024 photodiode matrix at 48 μm pixel pitch. Refractive MLAs with plano-convex lenses of 480 μm in diameter and pitch were selected resulting in a 55 x 105 lens matrix. The CMOS sensor is aligned on the focal plane of the MLA at 2.15mm distance. To separate individual microlens images an opaque multi-bore septum mask of 2.1mm in thickness and bore diameters of 400 μm at 480 μm pitch, aligned with the lens pattern, is placed between MLA and CMOS. Intrinsic spatial detector resolution and sensitivity was evaluated experimentally as a function of detector-object distance. Due to its small overall dimensions such detectors can be favorably packed for tomographic imaging (optical diffusion tomography, ODT) yielding complete 2 π field-of-view coverage. We also present a design study of a device intended to simultaneously image positron labeled substrates (positron emission tomography, PET) and optical molecular probes in small animals such as mice and rats. It consists of a cylindrical allocation of optical detector units which form an inner detector ring while PET detector blocks are mounted in radial extension, those gaining complementary information in a single, intrinsically coregistered experimental data acquisition study. Finally, in a second design study we propose a method for integrated optical and magnetic resonance imaging (MRI) which yields in vivo functional/molecular information that is intrinsically registered with the anatomy of the image object." @default.
- W2047546501 created "2016-06-24" @default.
- W2047546501 creator A5013765421 @default.
- W2047546501 creator A5059709728 @default.
- W2047546501 creator A5067052673 @default.
- W2047546501 creator A5086232111 @default.
- W2047546501 date "2007-07-05" @default.
- W2047546501 modified "2023-09-23" @default.
- W2047546501 title "A novel optical detector concept for dedicated and multi-modality in vivo small animal imaging" @default.
- W2047546501 doi "https://doi.org/10.1117/12.728500" @default.
- W2047546501 hasPublicationYear "2007" @default.
- W2047546501 type Work @default.
- W2047546501 sameAs 2047546501 @default.
- W2047546501 citedByCount "0" @default.
- W2047546501 crossrefType "proceedings-article" @default.
- W2047546501 hasAuthorship W2047546501A5013765421 @default.
- W2047546501 hasAuthorship W2047546501A5059709728 @default.
- W2047546501 hasAuthorship W2047546501A5067052673 @default.
- W2047546501 hasAuthorship W2047546501A5086232111 @default.
- W2047546501 hasConcept C120665830 @default.
- W2047546501 hasConcept C121332964 @default.
- W2047546501 hasConcept C150627866 @default.
- W2047546501 hasConcept C15336307 @default.
- W2047546501 hasConcept C155512908 @default.
- W2047546501 hasConcept C192560794 @default.
- W2047546501 hasConcept C192562407 @default.
- W2047546501 hasConcept C20788544 @default.
- W2047546501 hasConcept C34445779 @default.
- W2047546501 hasConcept C46362747 @default.
- W2047546501 hasConcept C49040817 @default.
- W2047546501 hasConcept C520434653 @default.
- W2047546501 hasConcept C751236 @default.
- W2047546501 hasConcept C76935873 @default.
- W2047546501 hasConcept C94915269 @default.
- W2047546501 hasConceptScore W2047546501C120665830 @default.
- W2047546501 hasConceptScore W2047546501C121332964 @default.
- W2047546501 hasConceptScore W2047546501C150627866 @default.
- W2047546501 hasConceptScore W2047546501C15336307 @default.
- W2047546501 hasConceptScore W2047546501C155512908 @default.
- W2047546501 hasConceptScore W2047546501C192560794 @default.
- W2047546501 hasConceptScore W2047546501C192562407 @default.
- W2047546501 hasConceptScore W2047546501C20788544 @default.
- W2047546501 hasConceptScore W2047546501C34445779 @default.
- W2047546501 hasConceptScore W2047546501C46362747 @default.
- W2047546501 hasConceptScore W2047546501C49040817 @default.
- W2047546501 hasConceptScore W2047546501C520434653 @default.
- W2047546501 hasConceptScore W2047546501C751236 @default.
- W2047546501 hasConceptScore W2047546501C76935873 @default.
- W2047546501 hasConceptScore W2047546501C94915269 @default.
- W2047546501 hasLocation W20475465011 @default.
- W2047546501 hasOpenAccess W2047546501 @default.
- W2047546501 hasPrimaryLocation W20475465011 @default.
- W2047546501 hasRelatedWork W1998862030 @default.
- W2047546501 hasRelatedWork W2027229323 @default.
- W2047546501 hasRelatedWork W2027354902 @default.
- W2047546501 hasRelatedWork W2047546501 @default.
- W2047546501 hasRelatedWork W2099015120 @default.
- W2047546501 hasRelatedWork W2106574814 @default.
- W2047546501 hasRelatedWork W2143589838 @default.
- W2047546501 hasRelatedWork W2207213958 @default.
- W2047546501 hasRelatedWork W2535634359 @default.
- W2047546501 hasRelatedWork W2992480247 @default.
- W2047546501 isParatext "false" @default.
- W2047546501 isRetracted "false" @default.
- W2047546501 magId "2047546501" @default.
- W2047546501 workType "article" @default.