FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2047546957> ?p ?o ?g. }

• W2047546957 endingPage "895" @default.
• W2047546957 startingPage "884" @default.
• W2047546957 abstract "BACKGROUND Metabolic imaging with positron emission tomography (PET) can detect tissue viability in clinical infarct regions. With appropriate tracer kinetic models and serial PET imaging, regional myocardial blood flow and rates of metabolism can now be quantified in patients with recent myocardial infarctions. METHODS AND RESULTS Serial PET imaging with [13N]ammonia, [11C]acetate, and 18F-deoxyglucose was performed in 22 patients with recent infarctions to measure regional blood flow (in milliliters per gram per minute), glucose metabolism (in micromoles per gram per minute), and oxidative metabolism (in clearance rate per minute). Hypoperfused clinical infarct regions were classified as PET mismatch if 18F was increased relative to 13N activity or PET match if 13N and 18F activities were reduced concordantly. Blood flows differed significantly between normal, mismatch, and match segments (0.83 +/- 0.20, 0.57 +/- 0.20, and 0.32 +/- 0.12 mL.g-1.min-1, respectively). The relation between oxidative metabolism and blood flow was piecewise linear and differed significantly between PET mismatch and PET match. Oxidative metabolism was less severely reduced than blood flow in mismatch regions but but reduced in proportion to blood flow in match regions. There was considerable overlap of blood flows between both types of PET segments. CONCLUSIONS Quantification of regional blood flow and substrate metabolism in postinfarction patients revealed alterations in the relation between substrate delivery and consumption demonstrated previously only in invasive animal experiments. The preserved oxidative metabolism in myocardium with PET mismatches may be ascribed to a regional increase in oxygen extraction. Such increase together with preserved glucose utilization may be the prerequisite for survival of ischemically injured myocardium." @default.
• W2047546957 created "2016-06-24" @default.
• W2047546957 creator A5001457381 @default.
• W2047546957 creator A5002877751 @default.
• W2047546957 creator A5005606378 @default.
• W2047546957 creator A5014832890 @default.
• W2047546957 creator A5015249625 @default.
• W2047546957 creator A5036918006 @default.
• W2047546957 creator A5049548593 @default.
• W2047546957 creator A5055785060 @default.
• W2047546957 creator A5064202007 @default.
• W2047546957 creator A5073532465 @default.
• W2047546957 date "1993-09-01" @default.
• W2047546957 modified "2023-10-10" @default.
• W2047546957 title "Regional blood flow, oxidative metabolism, and glucose utilization in patients with recent myocardial infarction." @default.
• W2047546957 cites W1856001453 @default.
• W2047546957 cites W1884634398 @default.
• W2047546957 cites W1966059564 @default.
• W2047546957 cites W1973612555 @default.
• W2047546957 cites W1982038828 @default.
• W2047546957 cites W2008630818 @default.
• W2047546957 cites W2010194527 @default.
• W2047546957 cites W2012733542 @default.
• W2047546957 cites W2015335570 @default.
• W2047546957 cites W2018877895 @default.
• W2047546957 cites W2020971669 @default.
• W2047546957 cites W2029150523 @default.
• W2047546957 cites W2042279710 @default.
• W2047546957 cites W2053945641 @default.
• W2047546957 cites W2054765812 @default.
• W2047546957 cites W2055598610 @default.
• W2047546957 cites W2066340356 @default.
• W2047546957 cites W2067991743 @default.
• W2047546957 cites W2068484619 @default.
• W2047546957 cites W2078059060 @default.
• W2047546957 cites W2085369096 @default.
• W2047546957 cites W2094321468 @default.
• W2047546957 cites W2163794208 @default.
• W2047546957 cites W2164562550 @default.
• W2047546957 cites W2410554790 @default.
• W2047546957 cites W2411881249 @default.
• W2047546957 cites W2530163185 @default.
• W2047546957 doi "https://doi.org/10.1161/01.cir.88.3.884" @default.
• W2047546957 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8353915" @default.
• W2047546957 hasPublicationYear "1993" @default.
• W2047546957 type Work @default.
• W2047546957 sameAs 2047546957 @default.
• W2047546957 citedByCount "90" @default.
• W2047546957 countsByYear W20475469572012 @default.
• W2047546957 countsByYear W20475469572013 @default.
• W2047546957 countsByYear W20475469572014 @default.
• W2047546957 countsByYear W20475469572016 @default.
• W2047546957 countsByYear W20475469572017 @default.
• W2047546957 countsByYear W20475469572018 @default.
• W2047546957 countsByYear W20475469572021 @default.
• W2047546957 countsByYear W20475469572022 @default.
• W2047546957 countsByYear W20475469572023 @default.
• W2047546957 crossrefType "journal-article" @default.
• W2047546957 hasAuthorship W2047546957A5001457381 @default.
• W2047546957 hasAuthorship W2047546957A5002877751 @default.
• W2047546957 hasAuthorship W2047546957A5005606378 @default.
• W2047546957 hasAuthorship W2047546957A5014832890 @default.
• W2047546957 hasAuthorship W2047546957A5015249625 @default.
• W2047546957 hasAuthorship W2047546957A5036918006 @default.
• W2047546957 hasAuthorship W2047546957A5049548593 @default.
• W2047546957 hasAuthorship W2047546957A5055785060 @default.
• W2047546957 hasAuthorship W2047546957A5064202007 @default.
• W2047546957 hasAuthorship W2047546957A5073532465 @default.
• W2047546957 hasBestOaLocation W20475469571 @default.
• W2047546957 hasConcept C126322002 @default.
• W2047546957 hasConcept C158846371 @default.
• W2047546957 hasConcept C164705383 @default.
• W2047546957 hasConcept C17093226 @default.
• W2047546957 hasConcept C185592680 @default.
• W2047546957 hasConcept C2775842073 @default.
• W2047546957 hasConcept C2777866211 @default.
• W2047546957 hasConcept C2779306644 @default.
• W2047546957 hasConcept C2989005 @default.
• W2047546957 hasConcept C2994198108 @default.
• W2047546957 hasConcept C500558357 @default.
• W2047546957 hasConcept C55493867 @default.
• W2047546957 hasConcept C57600042 @default.
• W2047546957 hasConcept C62231903 @default.
• W2047546957 hasConcept C71924100 @default.
• W2047546957 hasConceptScore W2047546957C126322002 @default.
• W2047546957 hasConceptScore W2047546957C158846371 @default.
• W2047546957 hasConceptScore W2047546957C164705383 @default.
• W2047546957 hasConceptScore W2047546957C17093226 @default.
• W2047546957 hasConceptScore W2047546957C185592680 @default.
• W2047546957 hasConceptScore W2047546957C2775842073 @default.
• W2047546957 hasConceptScore W2047546957C2777866211 @default.
• W2047546957 hasConceptScore W2047546957C2779306644 @default.
• W2047546957 hasConceptScore W2047546957C2989005 @default.
• W2047546957 hasConceptScore W2047546957C2994198108 @default.
• W2047546957 hasConceptScore W2047546957C500558357 @default.
• W2047546957 hasConceptScore W2047546957C55493867 @default.
• W2047546957 hasConceptScore W2047546957C57600042 @default.
• W2047546957 hasConceptScore W2047546957C62231903 @default.

• next