FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2047594735> ?p ?o ?g. }

• W2047594735 endingPage "3132" @default.
• W2047594735 startingPage "3127" @default.
• W2047594735 abstract "Disruption of glucagon-like peptide-1 (GLP-1) receptor signaling in mice results in mild glucose intolerance, principally due to elimination of the incretin effect of GLP-1. Despite the inhibitory effects of GLP-1 on food intake, 6- to 8-week-old GLP-1 receptor -/-(GLP-1R-/-) mice were not obese and did not exhibit disturbances of feeding behavior. As both diabetes and obesity frequently become more phenotypically evident in older rodents, we studied the consequences of aging and a high fat diet on glucose control and body weight in GLP-1R-/- mice. No evidence of obesity or deterioration in glucose control was detected in 11- and 16-month-old GLP-1R-/- mice (mean weight, 34.7 +/- 2.0, 30.5 +/- 1.5, and 34.6 +/- 2.8 g in male and 25.3 +/-1.6, 28.4 +/-1.2, and 31.9 +/- 2.9 g in female GLP-1R+/+, GLP-1R+/-, and GLP-1R-/- mice, respectively; P = NS). After 18 weeks of high fat feeding, GLP-1R-/- mice gained similar (males) or less (females) weight than age- and sex-matched CD1 controls. No significant deterioration in glucose tolerance was observed after high fat feeding in GLP-1R-/- mice. These observations demonstrate that long term disruption of GLP-1 signaling in the central nervous system and peripheral tissues of older mice is not associated with the development of obesity or deterioration in glucose homeostasis." @default.
• W2047594735 created "2016-06-24" @default.
• W2047594735 creator A5057472647 @default.
• W2047594735 creator A5087213411 @default.
• W2047594735 date "1998-07-01" @default.
• W2047594735 modified "2023-10-15" @default.
• W2047594735 title "Effects of Aging and a High Fat Diet on Body Weight and Glucose Tolerance in Glucagon-Like Peptide-1 Receptor−/− Mice*" @default.
• W2047594735 cites W1543470256 @default.
• W2047594735 cites W1963621734 @default.
• W2047594735 cites W1964212912 @default.
• W2047594735 cites W1966697925 @default.
• W2047594735 cites W1968939832 @default.
• W2047594735 cites W1975566161 @default.
• W2047594735 cites W1975756049 @default.
• W2047594735 cites W1989616977 @default.
• W2047594735 cites W1995223302 @default.
• W2047594735 cites W1999413356 @default.
• W2047594735 cites W2000465889 @default.
• W2047594735 cites W2002294810 @default.
• W2047594735 cites W2008411184 @default.
• W2047594735 cites W2013082477 @default.
• W2047594735 cites W2017690914 @default.
• W2047594735 cites W2022101780 @default.
• W2047594735 cites W2039423797 @default.
• W2047594735 cites W2041442731 @default.
• W2047594735 cites W2042845313 @default.
• W2047594735 cites W2044980718 @default.
• W2047594735 cites W2050046962 @default.
• W2047594735 cites W2055162678 @default.
• W2047594735 cites W2055718211 @default.
• W2047594735 cites W2074501705 @default.
• W2047594735 cites W2080128749 @default.
• W2047594735 cites W2081666098 @default.
• W2047594735 cites W2084534846 @default.
• W2047594735 cites W2108107144 @default.
• W2047594735 cites W2125036135 @default.
• W2047594735 cites W2125312207 @default.
• W2047594735 cites W2135514940 @default.
• W2047594735 cites W2153798846 @default.
• W2047594735 cites W2155633307 @default.
• W2047594735 cites W2156627717 @default.
• W2047594735 cites W2416022039 @default.
• W2047594735 cites W4237887793 @default.
• W2047594735 cites W4361745638 @default.
• W2047594735 doi "https://doi.org/10.1210/endo.139.7.6092" @default.
• W2047594735 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9645685" @default.
• W2047594735 hasPublicationYear "1998" @default.
• W2047594735 type Work @default.
• W2047594735 sameAs 2047594735 @default.
• W2047594735 citedByCount "71" @default.
• W2047594735 countsByYear W20475947352012 @default.
• W2047594735 countsByYear W20475947352013 @default.
• W2047594735 countsByYear W20475947352014 @default.
• W2047594735 countsByYear W20475947352015 @default.
• W2047594735 countsByYear W20475947352016 @default.
• W2047594735 countsByYear W20475947352017 @default.
• W2047594735 countsByYear W20475947352019 @default.
• W2047594735 countsByYear W20475947352020 @default.
• W2047594735 countsByYear W20475947352021 @default.
• W2047594735 countsByYear W20475947352022 @default.
• W2047594735 countsByYear W20475947352023 @default.
• W2047594735 crossrefType "journal-article" @default.
• W2047594735 hasAuthorship W2047594735A5057472647 @default.
• W2047594735 hasAuthorship W2047594735A5087213411 @default.
• W2047594735 hasBestOaLocation W20475947351 @default.
• W2047594735 hasConcept C126322002 @default.
• W2047594735 hasConcept C134018914 @default.
• W2047594735 hasConcept C170493617 @default.
• W2047594735 hasConcept C2776129832 @default.
• W2047594735 hasConcept C2776398474 @default.
• W2047594735 hasConcept C2777180221 @default.
• W2047594735 hasConcept C2777391703 @default.
• W2047594735 hasConcept C2778542361 @default.
• W2047594735 hasConcept C2778563252 @default.
• W2047594735 hasConcept C2778881409 @default.
• W2047594735 hasConcept C2779306644 @default.
• W2047594735 hasConcept C2780192938 @default.
• W2047594735 hasConcept C2780609358 @default.
• W2047594735 hasConcept C2780833929 @default.
• W2047594735 hasConcept C3018667095 @default.
• W2047594735 hasConcept C511355011 @default.
• W2047594735 hasConcept C555293320 @default.
• W2047594735 hasConcept C63645605 @default.
• W2047594735 hasConcept C71924100 @default.
• W2047594735 hasConcept C86803240 @default.
• W2047594735 hasConceptScore W2047594735C126322002 @default.
• W2047594735 hasConceptScore W2047594735C134018914 @default.
• W2047594735 hasConceptScore W2047594735C170493617 @default.
• W2047594735 hasConceptScore W2047594735C2776129832 @default.
• W2047594735 hasConceptScore W2047594735C2776398474 @default.
• W2047594735 hasConceptScore W2047594735C2777180221 @default.
• W2047594735 hasConceptScore W2047594735C2777391703 @default.
• W2047594735 hasConceptScore W2047594735C2778542361 @default.
• W2047594735 hasConceptScore W2047594735C2778563252 @default.
• W2047594735 hasConceptScore W2047594735C2778881409 @default.
• W2047594735 hasConceptScore W2047594735C2779306644 @default.
• W2047594735 hasConceptScore W2047594735C2780192938 @default.
• W2047594735 hasConceptScore W2047594735C2780609358 @default.

• next