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- W2047606975 abstract "The extraction studies and a one-step purification of the crude extract of Plumbago indica using silica-gel vacuum chromatography provided a plumbagin derivative-rich P. indica root extract (PPE). The PPE was standardised to contain total plumbagin derivatives not less than 13% w/w. Antibacterial activities of the standardised PPE and three naphthoquinones, plumbagin, elliptinone and 3,3'-biplumbagin, against Propionibacterium acnes, Staphylococcus aureus and Staphylococcus epidermidis were evaluated by using the microdilution assay. The bactericidal activities of the PPE against these bacteria were much stronger than those of elliptinone and 3,3'-biplumbagin and almost equal to those of plumbagin. Stability of the PPE was determined under various conditions through a period of four months. The PPE was stable over a period of four months when stored as a dried powder but only in a well-closed container protected from light under 4 ± 2°C." @default.
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- W2047606975 date "2014-01-31" @default.
- W2047606975 modified "2023-10-18" @default.
- W2047606975 title "Antibacterial activity of plumbagin derivative-rich <i>Plumbago indica</i> root extracts and chemical stability" @default.
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- W2047606975 doi "https://doi.org/10.1080/14786419.2013.879585" @default.
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