Matches in SemOpenAlex for { <https://semopenalex.org/work/W2047622746> ?p ?o ?g. }
- W2047622746 endingPage "10448" @default.
- W2047622746 startingPage "10438" @default.
- W2047622746 abstract "Spirochetes of the genus Borrelia include the tick-transmitted causative agents of Lyme disease and relapsing fever. They possess unusual genomes composed mainly of linear replicons terminated by closed DNA hairpin telomeres. Hairpin telomeres present an uninterrupted DNA chain to the replication machinery overcoming the 'end-replication problem' for the linear replicons. Hairpin telomeres are formed from inverted repeat replicated telomere junctions by the telomere resolvase, ResT. ResT uses a reaction mechanism similar to that of the type IB topoisomerases and tyrosine recombinases. We report here that ResT also possesses single-strand annealing activity and a limited ability to promote DNA strand exchange reactions on partial duplex substrates. This combination of activities suggests ResT is a nexus between the seemingly distinct processes of telomere resolution and homologous recombination. Implications for hairpin telomere replication and linear plasmid recombination, including antigenic variation, are discussed." @default.
- W2047622746 created "2016-06-24" @default.
- W2047622746 creator A5001821682 @default.
- W2047622746 creator A5033298143 @default.
- W2047622746 creator A5037756146 @default.
- W2047622746 date "2013-09-17" @default.
- W2047622746 modified "2023-10-14" @default.
- W2047622746 title "The telomere resolvase of the Lyme disease spirochete, Borrelia burgdorferi, promotes DNA single-strand annealing and strand exchange" @default.
- W2047622746 cites W119819143 @default.
- W2047622746 cites W1497256210 @default.
- W2047622746 cites W1525565041 @default.
- W2047622746 cites W1590546489 @default.
- W2047622746 cites W1600950270 @default.
- W2047622746 cites W1966666560 @default.
- W2047622746 cites W1970411207 @default.
- W2047622746 cites W1975286527 @default.
- W2047622746 cites W1982519372 @default.
- W2047622746 cites W1984626450 @default.
- W2047622746 cites W1993249060 @default.
- W2047622746 cites W1994199962 @default.
- W2047622746 cites W1995027904 @default.
- W2047622746 cites W2001895598 @default.
- W2047622746 cites W2013629751 @default.
- W2047622746 cites W2016708188 @default.
- W2047622746 cites W2017592299 @default.
- W2047622746 cites W2027802373 @default.
- W2047622746 cites W2029103031 @default.
- W2047622746 cites W2035273924 @default.
- W2047622746 cites W2035329781 @default.
- W2047622746 cites W2039319572 @default.
- W2047622746 cites W2041111848 @default.
- W2047622746 cites W2046241462 @default.
- W2047622746 cites W2048792961 @default.
- W2047622746 cites W2059320314 @default.
- W2047622746 cites W2069595322 @default.
- W2047622746 cites W2073247834 @default.
- W2047622746 cites W2078689375 @default.
- W2047622746 cites W2081284436 @default.
- W2047622746 cites W2081482870 @default.
- W2047622746 cites W2083198342 @default.
- W2047622746 cites W2086098426 @default.
- W2047622746 cites W2090659087 @default.
- W2047622746 cites W2092407519 @default.
- W2047622746 cites W2105281406 @default.
- W2047622746 cites W2111621826 @default.
- W2047622746 cites W2112657948 @default.
- W2047622746 cites W2112769025 @default.
- W2047622746 cites W2126361238 @default.
- W2047622746 cites W2129495960 @default.
- W2047622746 cites W2133290100 @default.
- W2047622746 cites W2138221072 @default.
- W2047622746 cites W2139095560 @default.
- W2047622746 cites W2144550200 @default.
- W2047622746 cites W2148501392 @default.
- W2047622746 cites W2152109513 @default.
- W2047622746 cites W2152260705 @default.
- W2047622746 cites W2159949846 @default.
- W2047622746 cites W2401652560 @default.
- W2047622746 cites W4242790321 @default.
- W2047622746 cites W641630426 @default.
- W2047622746 cites W7299969 @default.
- W2047622746 doi "https://doi.org/10.1093/nar/gkt832" @default.
- W2047622746 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3905847" @default.
- W2047622746 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24049070" @default.
- W2047622746 hasPublicationYear "2013" @default.
- W2047622746 type Work @default.
- W2047622746 sameAs 2047622746 @default.
- W2047622746 citedByCount "16" @default.
- W2047622746 countsByYear W20476227462014 @default.
- W2047622746 countsByYear W20476227462015 @default.
- W2047622746 countsByYear W20476227462016 @default.
- W2047622746 countsByYear W20476227462017 @default.
- W2047622746 countsByYear W20476227462018 @default.
- W2047622746 countsByYear W20476227462020 @default.
- W2047622746 countsByYear W20476227462021 @default.
- W2047622746 countsByYear W20476227462022 @default.
- W2047622746 countsByYear W20476227462023 @default.
- W2047622746 crossrefType "journal-article" @default.
- W2047622746 hasAuthorship W2047622746A5001821682 @default.
- W2047622746 hasAuthorship W2047622746A5033298143 @default.
- W2047622746 hasAuthorship W2047622746A5037756146 @default.
- W2047622746 hasBestOaLocation W20476227461 @default.
- W2047622746 hasConcept C102414288 @default.
- W2047622746 hasConcept C102744134 @default.
- W2047622746 hasConcept C104317684 @default.
- W2047622746 hasConcept C105793898 @default.
- W2047622746 hasConcept C141231307 @default.
- W2047622746 hasConcept C156695909 @default.
- W2047622746 hasConcept C159047783 @default.
- W2047622746 hasConcept C159654299 @default.
- W2047622746 hasConcept C177336024 @default.
- W2047622746 hasConcept C18103114 @default.
- W2047622746 hasConcept C202265312 @default.
- W2047622746 hasConcept C22744801 @default.
- W2047622746 hasConcept C2779159148 @default.
- W2047622746 hasConcept C2780508971 @default.
- W2047622746 hasConcept C4918238 @default.
- W2047622746 hasConcept C54355233 @default.