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• W2047643372 abstract "Mutation with Ser-83→Leu in gyrA gene was associated with the principal mutation for ciprofloxacin resistance in clinical isolates of Acinetobacter baumannii. Double mutation, Ser-83→Leu in gyrA gene and Ser-80→Leu in parC gene, was the most frequently detected among ciprofloxacin-resistant isolates. A novel mutation with Ser-80→Trp in parC gene, in addition to mutation in gyrA gene, was associated with a high-level ciprofloxacin resistance. These results suggested that the presence of an additional mutation in the parC gene contributed to a higher-level of ciprofloxacin resistance than a single mutation in the gyrA gene (geometric mean MICs of ciprofloxacin, 44.1 versus 16 μg/ml, P<0.05)." @default.
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• W2047643372 date "2005-07-01" @default.
• W2047643372 modified "2023-10-17" @default.
• W2047643372 title "Mutations in the<i>gyrA</i>and<i>parC</i>Genes in Ciprofloxacin-Resistant Clinical Isolates of<i>Acinetobacter baumannii</i>in Korea" @default.
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• W2047643372 doi "https://doi.org/10.1111/j.1348-0421.2005.tb03643.x" @default.
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