Matches in SemOpenAlex for { <https://semopenalex.org/work/W2047647580> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2047647580 abstract "A new polymorphic locus of the horse which has several unusual properties is described. The suggested name for the locus is ELY-2. The gene product of one allele at this locus, designated ELY-2.1, has been identified with antisera raised as a result of pregnancy. Antibody to ELY-2.1 was first detected on day 55 after conception in the serum of a mare in first pregnancy. This early onset of antibody is similar to that seen for antibody to ELA antigens, and suggests that the source of the antigenic stimulus may be the tissue of the equine endometrial cups. The antisera identifying ELY-2.1 are cytotoxic and kill all peripheral blood lymphocytes from horses carrying the antigen. ELY-2.1 is a cell surface molecule expressed on lymphocytes, erythrocytes, and platelets. Other cell types have not been investigated. The overall phenotypic frequency of ELY-2.1 in several horse breeds was 16%. The ELY-2.1 antigen is controlled by an autosomal, dominant gene which is not coded by the ELA region (the major histocompatibility complex of the horse), nor is it identical to the ELY-1 locus, which codes for another cell surface alloantigen of equine lymphocytes. Stimulator cells carrying ELY-2.1 did not induce proliferation of ELY-2.1 negative responder cells in mixed cultures of horse lymphocytes. Attempts to raise alloantisera to other alleles of the ELY-2 locus through immunization with lymphocytes were unsuccessful. It is possible that the alternate allele(s) does not code for a gene product which is expressed. The function and biochemical nature of the ELY-2.1 molecule are unknown." @default.
- W2047647580 created "2016-06-24" @default.
- W2047647580 creator A5004134579 @default.
- W2047647580 date "2009-04-24" @default.
- W2047647580 modified "2023-09-26" @default.
- W2047647580 title "Lymphocyte alloantigens of the horse. III. ELY-2.1: a lymphocyte alloantigen not coded for by the MHC" @default.
- W2047647580 cites W1584072539 @default.
- W2047647580 cites W1917952603 @default.
- W2047647580 cites W1964091729 @default.
- W2047647580 cites W1967034208 @default.
- W2047647580 cites W1971544770 @default.
- W2047647580 cites W1994484088 @default.
- W2047647580 cites W1999629444 @default.
- W2047647580 cites W2012666695 @default.
- W2047647580 cites W2030169939 @default.
- W2047647580 cites W2033848809 @default.
- W2047647580 cites W2047668599 @default.
- W2047647580 cites W2052731591 @default.
- W2047647580 cites W2065280352 @default.
- W2047647580 cites W2069976423 @default.
- W2047647580 cites W2089310938 @default.
- W2047647580 cites W2093793816 @default.
- W2047647580 cites W2094374140 @default.
- W2047647580 cites W2155448462 @default.
- W2047647580 cites W4233741249 @default.
- W2047647580 doi "https://doi.org/10.1111/j.1365-2052.1984.tb01105.x" @default.
- W2047647580 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6497057" @default.
- W2047647580 hasPublicationYear "2009" @default.
- W2047647580 type Work @default.
- W2047647580 sameAs 2047647580 @default.
- W2047647580 citedByCount "22" @default.
- W2047647580 countsByYear W20476475802012 @default.
- W2047647580 countsByYear W20476475802020 @default.
- W2047647580 crossrefType "journal-article" @default.
- W2047647580 hasAuthorship W2047647580A5004134579 @default.
- W2047647580 hasConcept C104317684 @default.
- W2047647580 hasConcept C147483822 @default.
- W2047647580 hasConcept C151730666 @default.
- W2047647580 hasConcept C153911025 @default.
- W2047647580 hasConcept C154317977 @default.
- W2047647580 hasConcept C159654299 @default.
- W2047647580 hasConcept C180754005 @default.
- W2047647580 hasConcept C188280979 @default.
- W2047647580 hasConcept C202751555 @default.
- W2047647580 hasConcept C202965653 @default.
- W2047647580 hasConcept C203014093 @default.
- W2047647580 hasConcept C207936829 @default.
- W2047647580 hasConcept C2777761686 @default.
- W2047647580 hasConcept C2780762169 @default.
- W2047647580 hasConcept C54355233 @default.
- W2047647580 hasConcept C84597430 @default.
- W2047647580 hasConcept C86803240 @default.
- W2047647580 hasConcept C91523082 @default.
- W2047647580 hasConceptScore W2047647580C104317684 @default.
- W2047647580 hasConceptScore W2047647580C147483822 @default.
- W2047647580 hasConceptScore W2047647580C151730666 @default.
- W2047647580 hasConceptScore W2047647580C153911025 @default.
- W2047647580 hasConceptScore W2047647580C154317977 @default.
- W2047647580 hasConceptScore W2047647580C159654299 @default.
- W2047647580 hasConceptScore W2047647580C180754005 @default.
- W2047647580 hasConceptScore W2047647580C188280979 @default.
- W2047647580 hasConceptScore W2047647580C202751555 @default.
- W2047647580 hasConceptScore W2047647580C202965653 @default.
- W2047647580 hasConceptScore W2047647580C203014093 @default.
- W2047647580 hasConceptScore W2047647580C207936829 @default.
- W2047647580 hasConceptScore W2047647580C2777761686 @default.
- W2047647580 hasConceptScore W2047647580C2780762169 @default.
- W2047647580 hasConceptScore W2047647580C54355233 @default.
- W2047647580 hasConceptScore W2047647580C84597430 @default.
- W2047647580 hasConceptScore W2047647580C86803240 @default.
- W2047647580 hasConceptScore W2047647580C91523082 @default.
- W2047647580 hasLocation W20476475801 @default.
- W2047647580 hasLocation W20476475802 @default.
- W2047647580 hasOpenAccess W2047647580 @default.
- W2047647580 hasPrimaryLocation W20476475801 @default.
- W2047647580 hasRelatedWork W1973088414 @default.
- W2047647580 hasRelatedWork W1982316259 @default.
- W2047647580 hasRelatedWork W1984783916 @default.
- W2047647580 hasRelatedWork W1990946110 @default.
- W2047647580 hasRelatedWork W2006136087 @default.
- W2047647580 hasRelatedWork W2009952043 @default.
- W2047647580 hasRelatedWork W2026594202 @default.
- W2047647580 hasRelatedWork W2047668599 @default.
- W2047647580 hasRelatedWork W2076924595 @default.
- W2047647580 hasRelatedWork W2140847347 @default.
- W2047647580 isParatext "false" @default.
- W2047647580 isRetracted "false" @default.
- W2047647580 magId "2047647580" @default.
- W2047647580 workType "article" @default.