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- W2047665004 abstract "The effect of NMDA receptor antagonist phencyclidine (PCP) on expression of cyclooxygenase (COX)-2 mRNA in the rat brain was studied. Administration of PCP (12.5, 25 or 50 mg/kg, i.p., 6 h) caused marked induction of COX-2 mRNA and heat shock gene hsp-70 mRNA, a marker of neuronal injury, in the retrosplenial cortex, in a dose-dependent manner. These results suggest that COX-2 may play a role in the neurotoxicity of NMDA receptor antagonists." @default.
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- W2047665004 date "1997-07-01" @default.
- W2047665004 modified "2023-09-27" @default.
- W2047665004 title "Expression of cyclooxygenase-2 mRNA in rat retrosplenial cortex following administration of phencyclidine" @default.
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- W2047665004 doi "https://doi.org/10.1016/s0006-8993(97)00505-2" @default.
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