FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2047710107> ?p ?o ?g. }

• W2047710107 abstract "Background: Adenoid cystic carcinoma (AdCC) displays morphological diversity within its characteristic tumor cell nests, which are primarily classified into tubular, cribriform, and solid patterns. Such histological diversity should result from the proportional proliferation between neoplastic myoepithelial cells (NMC)/basal cells and ductal epithelial cells. The aim of this study was to clarify the relationship between this morphological diversity and the development of AdCC in the salivary gland using double immunostaining with monoclonal antibodies to p16 and p63 gene products. Methods: We examined 10 samples of formalin-fixed, paraffin-embedded AdCC tissues. Results: In the normal salivary gland, p16 protein (P16) was not expressed in any cells, whereas p63 protein (P63)-positivities were observed in ductal basal cells and in acinar myoepithelial cells. In AdCC foci showing the tubular pattern, P16 expression was localized in the inner cells of the ductal structure, while P63 was localized in the outer NMC of them within the same sections. In tumor foci with the cribriform pattern, P16 was expressed in several cells forming pseudocysts and in some of the inner cells. P63 was expressed in many cells in the cancer nests. In those with the solid pattern, P16 and P63 were intermixed within the same foci. Conclusions: Thus, the double immunohistochemistry for P16 and P63 was useful for observing the morphological diversity of AdCC cells within the same foci on the same tissue section. These data suggest that P16 and P63 may play important roles in the morphological diversity and development of AdCC tissue architectures." @default.
• W2047710107 created "2016-06-24" @default.
• W2047710107 creator A5001107844 @default.
• W2047710107 creator A5033206734 @default.
• W2047710107 creator A5068981310 @default.
• W2047710107 date "2011-01-01" @default.
• W2047710107 modified "2023-09-24" @default.
• W2047710107 title "The histological diversity of adenoid cystic carcinoma demonstrated by double immunohistochemistry for p16 and p63 gene products" @default.
• W2047710107 cites W1519627309 @default.
• W2047710107 cites W1978109673 @default.
• W2047710107 cites W1979199368 @default.
• W2047710107 cites W1980636252 @default.
• W2047710107 cites W1986011832 @default.
• W2047710107 cites W1986771614 @default.
• W2047710107 cites W1993970552 @default.
• W2047710107 cites W1994298393 @default.
• W2047710107 cites W1996239347 @default.
• W2047710107 cites W2008160066 @default.
• W2047710107 cites W2021982612 @default.
• W2047710107 cites W2025869795 @default.
• W2047710107 cites W2029056875 @default.
• W2047710107 cites W2052787443 @default.
• W2047710107 cites W2062304575 @default.
• W2047710107 cites W2063711240 @default.
• W2047710107 cites W2064458151 @default.
• W2047710107 cites W2065512897 @default.
• W2047710107 cites W2085805626 @default.
• W2047710107 cites W2089556772 @default.
• W2047710107 cites W2098030075 @default.
• W2047710107 cites W2106355114 @default.
• W2047710107 cites W2145109253 @default.
• W2047710107 cites W2147060481 @default.
• W2047710107 cites W2149934092 @default.
• W2047710107 cites W2276290368 @default.
• W2047710107 cites W2301787246 @default.
• W2047710107 cites W79903929 @default.
• W2047710107 doi "https://doi.org/10.3353/omp.16.9" @default.
• W2047710107 hasPublicationYear "2011" @default.
• W2047710107 type Work @default.
• W2047710107 sameAs 2047710107 @default.
• W2047710107 citedByCount "1" @default.
• W2047710107 countsByYear W20477101072020 @default.
• W2047710107 crossrefType "journal-article" @default.
• W2047710107 hasAuthorship W2047710107A5001107844 @default.
• W2047710107 hasAuthorship W2047710107A5033206734 @default.
• W2047710107 hasAuthorship W2047710107A5068981310 @default.
• W2047710107 hasBestOaLocation W20477101071 @default.
• W2047710107 hasConcept C140884156 @default.
• W2047710107 hasConcept C142724271 @default.
• W2047710107 hasConcept C159654299 @default.
• W2047710107 hasConcept C203014093 @default.
• W2047710107 hasConcept C204232928 @default.
• W2047710107 hasConcept C2777546739 @default.
• W2047710107 hasConcept C2778148616 @default.
• W2047710107 hasConcept C2778937882 @default.
• W2047710107 hasConcept C2779231225 @default.
• W2047710107 hasConcept C2781163425 @default.
• W2047710107 hasConcept C2909818935 @default.
• W2047710107 hasConcept C40677261 @default.
• W2047710107 hasConcept C4224716 @default.
• W2047710107 hasConcept C542903549 @default.
• W2047710107 hasConcept C71924100 @default.
• W2047710107 hasConcept C86803240 @default.
• W2047710107 hasConceptScore W2047710107C140884156 @default.
• W2047710107 hasConceptScore W2047710107C142724271 @default.
• W2047710107 hasConceptScore W2047710107C159654299 @default.
• W2047710107 hasConceptScore W2047710107C203014093 @default.
• W2047710107 hasConceptScore W2047710107C204232928 @default.
• W2047710107 hasConceptScore W2047710107C2777546739 @default.
• W2047710107 hasConceptScore W2047710107C2778148616 @default.
• W2047710107 hasConceptScore W2047710107C2778937882 @default.
• W2047710107 hasConceptScore W2047710107C2779231225 @default.
• W2047710107 hasConceptScore W2047710107C2781163425 @default.
• W2047710107 hasConceptScore W2047710107C2909818935 @default.
• W2047710107 hasConceptScore W2047710107C40677261 @default.
• W2047710107 hasConceptScore W2047710107C4224716 @default.
• W2047710107 hasConceptScore W2047710107C542903549 @default.
• W2047710107 hasConceptScore W2047710107C71924100 @default.
• W2047710107 hasConceptScore W2047710107C86803240 @default.
• W2047710107 hasLocation W20477101071 @default.
• W2047710107 hasOpenAccess W2047710107 @default.
• W2047710107 hasPrimaryLocation W20477101071 @default.
• W2047710107 hasRelatedWork W1969408072 @default.
• W2047710107 hasRelatedWork W1973991924 @default.
• W2047710107 hasRelatedWork W1975717111 @default.
• W2047710107 hasRelatedWork W1976143198 @default.
• W2047710107 hasRelatedWork W1978353239 @default.
• W2047710107 hasRelatedWork W1986771614 @default.
• W2047710107 hasRelatedWork W1999936548 @default.
• W2047710107 hasRelatedWork W2010993260 @default.
• W2047710107 hasRelatedWork W2013199356 @default.
• W2047710107 hasRelatedWork W2036408338 @default.
• W2047710107 hasRelatedWork W2064342598 @default.
• W2047710107 hasRelatedWork W2065512897 @default.
• W2047710107 hasRelatedWork W2071266480 @default.
• W2047710107 hasRelatedWork W2120275912 @default.
• W2047710107 hasRelatedWork W2405351071 @default.
• W2047710107 hasRelatedWork W2414038052 @default.
• W2047710107 hasRelatedWork W2416897938 @default.
• W2047710107 hasRelatedWork W2417390540 @default.

• next