FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2047730892> ?p ?o ?g. }

• W2047730892 abstract "Abstract Apolipoprotein (apoB) plays a fundamental role in the transport and metabolism of plasma triacylglycerols (TAGs) and cholesterol. Several apoB polymorphic sites have been studied for their potential use as markers for coronary heart disease in the population. In view of the importance of apoB in postprandial metabolism, our objective was to determine whether the presence of the ‐516C/T polymorphism in the APOB gene promoter could influence postprandial lipoprotein metabolism in healthy subjects. Forty‐seven volunteers who were homozygous for the E3 allele at the APOE gene were selected (30 homozygous for the common genotype (C/C) and 17 heterozygotes for the ‐516T allele (C/T). They were given a fat‐rich meal containing 1 g fat and 7 mg cholesterol per kg body weight and vitamin A 60,000 IU/m 2 body surface. Fat accounted for 60% of calories, and protein and carbohydrates for 15 and 25% of energy, respectively. Blood samples were taken at time 0, every 1 h until 6 h, and every 2.5 h until 11 h. Total cholesterol and TAGs in plasma, and cholesterol, TAGs and retinyl palmitate in triacylglycerol‐rich lipoproteins (large and small triacylglycerol‐rich lipoproteins) were determined by ultracentrifugation. Individuals carrying the C/T genotype presented greater postprandial concentrations of TAGs in small triacylglycerol‐rich lipoproteins than did carriers of the C/C genotype ( P = 0.022). Moreover, C/T individuals presented higher concentrations of plasma TAGs during the postprandial period than did C/C subjects ( P = 0.039). No other statistically significant genotype‐related differences for other parameters were observed. These results suggest that the presence of the genotype C/T is associated with a higher postprandial response. Thus, the allele variability in the ‐516C/T polymorphism in the APOB gene promoter may partly explain the interindividual differences in postprandial lipemic response in healthy subjects." @default.
• W2047730892 created "2016-06-24" @default.
• W2047730892 creator A5003105778 @default.
• W2047730892 creator A5018093575 @default.
• W2047730892 creator A5027327306 @default.
• W2047730892 creator A5053271087 @default.
• W2047730892 creator A5056560096 @default.
• W2047730892 creator A5061501253 @default.
• W2047730892 creator A5072047182 @default.
• W2047730892 creator A5072074958 @default.
• W2047730892 creator A5081654489 @default.
• W2047730892 date "2007-02-10" @default.
• W2047730892 modified "2023-10-12" @default.
• W2047730892 title "Postprandial Lipemia is Modified by the Presence of the <i>APOB</i> ‐516C/T Polymorphism in a Healthy Caucasian Population" @default.
• W2047730892 cites W1527062163 @default.
• W2047730892 cites W1555219681 @default.
• W2047730892 cites W1860487341 @default.
• W2047730892 cites W1906920003 @default.
• W2047730892 cites W1933969153 @default.
• W2047730892 cites W1946263363 @default.
• W2047730892 cites W1972638452 @default.
• W2047730892 cites W1982368308 @default.
• W2047730892 cites W1990953214 @default.
• W2047730892 cites W2018944148 @default.
• W2047730892 cites W2020925755 @default.
• W2047730892 cites W2022129993 @default.
• W2047730892 cites W2037408127 @default.
• W2047730892 cites W2041978226 @default.
• W2047730892 cites W2046241874 @default.
• W2047730892 cites W2048851507 @default.
• W2047730892 cites W2052820569 @default.
• W2047730892 cites W2055161059 @default.
• W2047730892 cites W2059966241 @default.
• W2047730892 cites W2069382585 @default.
• W2047730892 cites W2072476641 @default.
• W2047730892 cites W2073404106 @default.
• W2047730892 cites W2088859305 @default.
• W2047730892 cites W2095885613 @default.
• W2047730892 cites W2102302576 @default.
• W2047730892 cites W2109020055 @default.
• W2047730892 cites W2118313918 @default.
• W2047730892 cites W2118375178 @default.
• W2047730892 cites W2118799974 @default.
• W2047730892 cites W2127626398 @default.
• W2047730892 cites W2133601187 @default.
• W2047730892 cites W2134093194 @default.
• W2047730892 cites W2183531925 @default.
• W2047730892 cites W2228000409 @default.
• W2047730892 cites W2345192228 @default.
• W2047730892 cites W2994309148 @default.
• W2047730892 cites W4240625608 @default.
• W2047730892 cites W4246204080 @default.
• W2047730892 cites W4246242698 @default.
• W2047730892 doi "https://doi.org/10.1007/s11745-007-3027-7" @default.
• W2047730892 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17393220" @default.
• W2047730892 hasPublicationYear "2007" @default.
• W2047730892 type Work @default.
• W2047730892 sameAs 2047730892 @default.
• W2047730892 citedByCount "12" @default.
• W2047730892 countsByYear W20477308922012 @default.
• W2047730892 countsByYear W20477308922014 @default.
• W2047730892 countsByYear W20477308922020 @default.
• W2047730892 countsByYear W20477308922021 @default.
• W2047730892 crossrefType "journal-article" @default.
• W2047730892 hasAuthorship W2047730892A5003105778 @default.
• W2047730892 hasAuthorship W2047730892A5018093575 @default.
• W2047730892 hasAuthorship W2047730892A5027327306 @default.
• W2047730892 hasAuthorship W2047730892A5053271087 @default.
• W2047730892 hasAuthorship W2047730892A5056560096 @default.
• W2047730892 hasAuthorship W2047730892A5061501253 @default.
• W2047730892 hasAuthorship W2047730892A5072047182 @default.
• W2047730892 hasAuthorship W2047730892A5072074958 @default.
• W2047730892 hasAuthorship W2047730892A5081654489 @default.
• W2047730892 hasConcept C104317684 @default.
• W2047730892 hasConcept C11772777 @default.
• W2047730892 hasConcept C126322002 @default.
• W2047730892 hasConcept C134018914 @default.
• W2047730892 hasConcept C135763542 @default.
• W2047730892 hasConcept C180754005 @default.
• W2047730892 hasConcept C22894154 @default.
• W2047730892 hasConcept C2778163477 @default.
• W2047730892 hasConcept C2778199505 @default.
• W2047730892 hasConcept C2779306644 @default.
• W2047730892 hasConcept C2780072125 @default.
• W2047730892 hasConcept C2908647359 @default.
• W2047730892 hasConcept C382228 @default.
• W2047730892 hasConcept C55493867 @default.
• W2047730892 hasConcept C62746215 @default.
• W2047730892 hasConcept C71924100 @default.
• W2047730892 hasConcept C8243546 @default.
• W2047730892 hasConcept C86803240 @default.
• W2047730892 hasConcept C99454951 @default.
• W2047730892 hasConceptScore W2047730892C104317684 @default.
• W2047730892 hasConceptScore W2047730892C11772777 @default.
• W2047730892 hasConceptScore W2047730892C126322002 @default.
• W2047730892 hasConceptScore W2047730892C134018914 @default.
• W2047730892 hasConceptScore W2047730892C135763542 @default.
• W2047730892 hasConceptScore W2047730892C180754005 @default.
• W2047730892 hasConceptScore W2047730892C22894154 @default.
• W2047730892 hasConceptScore W2047730892C2778163477 @default.

• next