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- W2047753682 abstract "The effect of mefloquine, a new antimalarial compound, on the immune response in mice was studied in vitro and in vivo. Slight inhibition of mitogen-induced lymphocyte proliferative responses was observed at a concentration of 1 μg/ml, and marked cytotoxicity at 4 μ/ml. In contrast, a higher proportion of human lymphocytes remained viable at the same concentration of mefloquine. Antibody responses to sheep erythrocytes were impaired in mice receiving a total dose of 60 mg/kg. At this dosage schedule, delayed-type hypersensitivity responses to the same antigen were not affected." @default.
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- W2047753682 title "Effect of mefloquine on the immune response in mice" @default.
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- W2047753682 doi "https://doi.org/10.1016/0035-9203(79)90160-3" @default.
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