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- W2047808197 abstract "In this paper, different electromigration methods used to monitor drugs and polymers released from drug delivery systems are reviewed. First, an introduction to the most typical arrangements used as drug delivery systems (e.g., polymer-drug covalent conjugates, membrane or matrix-based devices) is presented. Next, the principles of different capillary electromigration procedures are discussed, followed by a revision on the different procedures employed to monitor the release of drugs and the degradation or solubilization of the polymeric matrices from drug delivery systems during both in vitro and in vivo assays. A critical comparison between these capillary electrophoretic methods and the more common chromatographic methods employed to analyze drugs and polymers from drug delivery systems is presented. Finally, future outlooks of these electromigration procedures in the controlled release field are discussed." @default.
- W2047808197 created "2016-06-24" @default.
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- W2047808197 date "2003-11-01" @default.
- W2047808197 modified "2023-10-18" @default.
- W2047808197 title "Drug delivery systems: polymers and drugs monitored by capillary electromigration methods" @default.
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- W2047808197 doi "https://doi.org/10.1016/s1570-0232(03)00430-6" @default.
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