FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2047810146> ?p ?o ?g. }

• W2047810146 endingPage "198" @default.
• W2047810146 startingPage "187" @default.
• W2047810146 abstract "Herpes Simplex Virus (HSV) establishes a latent infection within sensory neurons and periodically reactivates in response to stress. HSV's ability to inhabit neurons for the life of the host involves a number of virally encoded functions that tightly regulate the latency-reactivation cycle, preventing uncontrolled spread of reactivating virus and large-scale death of neurons. The HSV latency-associated transcript (LAT) is a complex transcription unit expressed primarily in neurons containing latent genomes. While mutational analyses indicate LAT is nonessential for viral replication, the 5' exon of LAT greatly enhances reactivation. Several studies have also identified LAT mutations that reduce establishment of latency and enhance virulence. Recently, LAT has also been shown to inhibit cell death through by blocking caspase-8 and caspase-9 pathways. While blocking apoptosis is not essential for either establishment of latency or reactivation, it likely augments these processes and may contribute to HSV's long-term persistence and spread." @default.
• W2047810146 created "2016-06-24" @default.
• W2047810146 creator A5001365559 @default.
• W2047810146 date "2004-01-01" @default.
• W2047810146 modified "2023-10-16" @default.
• W2047810146 title "HSV LAT AND NEURONAL SURVIVAL" @default.
• W2047810146 cites W1493378177 @default.
• W2047810146 cites W1559448834 @default.
• W2047810146 cites W1783529936 @default.
• W2047810146 cites W1944137027 @default.
• W2047810146 cites W1991010205 @default.
• W2047810146 cites W1997624180 @default.
• W2047810146 cites W2010491850 @default.
• W2047810146 cites W2031688775 @default.
• W2047810146 cites W2031791450 @default.
• W2047810146 cites W2037047850 @default.
• W2047810146 cites W2039026634 @default.
• W2047810146 cites W2043117997 @default.
• W2047810146 cites W2087208900 @default.
• W2047810146 cites W2098308748 @default.
• W2047810146 cites W2119606579 @default.
• W2047810146 cites W2126134216 @default.
• W2047810146 cites W2127846162 @default.
• W2047810146 cites W2131792187 @default.
• W2047810146 cites W2133865307 @default.
• W2047810146 cites W2138965300 @default.
• W2047810146 cites W2141955811 @default.
• W2047810146 cites W2151331859 @default.
• W2047810146 cites W2162751422 @default.
• W2047810146 cites W2163424373 @default.
• W2047810146 cites W2168808708 @default.
• W2047810146 cites W265458114 @default.
• W2047810146 doi "https://doi.org/10.1080/08830180490265592" @default.
• W2047810146 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14690860" @default.
• W2047810146 hasPublicationYear "2004" @default.
• W2047810146 type Work @default.
• W2047810146 sameAs 2047810146 @default.
• W2047810146 citedByCount "80" @default.
• W2047810146 countsByYear W20478101462012 @default.
• W2047810146 countsByYear W20478101462013 @default.
• W2047810146 countsByYear W20478101462014 @default.
• W2047810146 countsByYear W20478101462015 @default.
• W2047810146 countsByYear W20478101462016 @default.
• W2047810146 countsByYear W20478101462017 @default.
• W2047810146 countsByYear W20478101462018 @default.
• W2047810146 countsByYear W20478101462019 @default.
• W2047810146 countsByYear W20478101462020 @default.
• W2047810146 countsByYear W20478101462021 @default.
• W2047810146 countsByYear W20478101462022 @default.
• W2047810146 countsByYear W20478101462023 @default.
• W2047810146 crossrefType "journal-article" @default.
• W2047810146 hasAuthorship W2047810146A5001365559 @default.
• W2047810146 hasConcept C104317684 @default.
• W2047810146 hasConcept C119599485 @default.
• W2047810146 hasConcept C127413603 @default.
• W2047810146 hasConcept C138885662 @default.
• W2047810146 hasConcept C140704245 @default.
• W2047810146 hasConcept C159047783 @default.
• W2047810146 hasConcept C179926584 @default.
• W2047810146 hasConcept C190283241 @default.
• W2047810146 hasConcept C2522874641 @default.
• W2047810146 hasConcept C2778852064 @default.
• W2047810146 hasConcept C2781196997 @default.
• W2047810146 hasConcept C31573885 @default.
• W2047810146 hasConcept C41895202 @default.
• W2047810146 hasConcept C54355233 @default.
• W2047810146 hasConcept C60987743 @default.
• W2047810146 hasConcept C82876162 @default.
• W2047810146 hasConcept C86803240 @default.
• W2047810146 hasConceptScore W2047810146C104317684 @default.
• W2047810146 hasConceptScore W2047810146C119599485 @default.
• W2047810146 hasConceptScore W2047810146C127413603 @default.
• W2047810146 hasConceptScore W2047810146C138885662 @default.
• W2047810146 hasConceptScore W2047810146C140704245 @default.
• W2047810146 hasConceptScore W2047810146C159047783 @default.
• W2047810146 hasConceptScore W2047810146C179926584 @default.
• W2047810146 hasConceptScore W2047810146C190283241 @default.
• W2047810146 hasConceptScore W2047810146C2522874641 @default.
• W2047810146 hasConceptScore W2047810146C2778852064 @default.
• W2047810146 hasConceptScore W2047810146C2781196997 @default.
• W2047810146 hasConceptScore W2047810146C31573885 @default.
• W2047810146 hasConceptScore W2047810146C41895202 @default.
• W2047810146 hasConceptScore W2047810146C54355233 @default.
• W2047810146 hasConceptScore W2047810146C60987743 @default.
• W2047810146 hasConceptScore W2047810146C82876162 @default.
• W2047810146 hasConceptScore W2047810146C86803240 @default.
• W2047810146 hasIssue "1-2" @default.
• W2047810146 hasLocation W20478101461 @default.
• W2047810146 hasLocation W20478101462 @default.
• W2047810146 hasOpenAccess W2047810146 @default.
• W2047810146 hasPrimaryLocation W20478101461 @default.
• W2047810146 hasRelatedWork W1223737510 @default.
• W2047810146 hasRelatedWork W2035177505 @default.
• W2047810146 hasRelatedWork W2075399742 @default.
• W2047810146 hasRelatedWork W2122466812 @default.
• W2047810146 hasRelatedWork W2122893310 @default.
• W2047810146 hasRelatedWork W2159527899 @default.
• W2047810146 hasRelatedWork W2165613721 @default.

• next