FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2047810742> ?p ?o ?g. }

• W2047810742 endingPage "320" @default.
• W2047810742 startingPage "311" @default.
• W2047810742 abstract "Cortisol is a major stress hormone in fish and is known, under normal or stressful conditions, to affect several physiological processes including growth and immunity. Thus, efforts have been made for several cultured finfish species, including the Atlantic cod, to determine whether fish with a high or low cortisol response to stress can be identified and selected. However, we have a limited understanding of the mechanisms that determine these two phenotypes. Thus, we measured total and free plasma cortisol levels in high and low responding cod when subjected to a 30 s handling stress, and the mRNA expression of four key genes in the glucocorticoid (i.e. cortisol) stress axis both pre- and post-stress. The cortisol data is consistent with our previous findings for cod, with high responding (HR) fish having ∼3-fold higher total and free plasma cortisol levels when compared to low responding (LR) fish. Three of the transcripts studied encode key proteins involved in steroidogenesis (StAR, P450scc and 3βHSD), and the constitutive mRNA expression of all three genes was significantly higher (∼2-fold) in the head kidney of HR fish when compared to LR cod. The other gene of interest was the glucocorticoid receptor (GR). We partly cloned and characterized a cDNA from Atlantic cod likely to be this fish’s ortholog of the teleost GR1, and showed that while there was no difference in hepatic constitutive GR mRNA expression between groups, HR fish had liver GR mRNA levels that were significantly (1.8-fold) higher at 3 h post-stress as compared to LR fish. Our results suggest that the different magnitude of cortisol response between LR and HR fish is at least partially determined by the capacity of the interrenal tissue to produce steroids." @default.
• W2047810742 created "2016-06-24" @default.
• W2047810742 creator A5005183831 @default.
• W2047810742 creator A5008019045 @default.
• W2047810742 creator A5014627755 @default.
• W2047810742 creator A5020184311 @default.
• W2047810742 creator A5034232080 @default.
• W2047810742 date "2012-01-01" @default.
• W2047810742 modified "2023-10-18" @default.
• W2047810742 title "The mRNA expression of cortisol axis related genes differs in Atlantic cod (Gadus morhua) categorized as high or low responders" @default.
• W2047810742 cites W1969425845 @default.
• W2047810742 cites W1972469808 @default.
• W2047810742 cites W1975572803 @default.
• W2047810742 cites W1979122371 @default.
• W2047810742 cites W1985157866 @default.
• W2047810742 cites W1991024712 @default.
• W2047810742 cites W1994055552 @default.
• W2047810742 cites W1994056363 @default.
• W2047810742 cites W1999284607 @default.
• W2047810742 cites W2008183439 @default.
• W2047810742 cites W2009734833 @default.
• W2047810742 cites W2012144992 @default.
• W2047810742 cites W2013042216 @default.
• W2047810742 cites W2018198771 @default.
• W2047810742 cites W2024632204 @default.
• W2047810742 cites W2025099925 @default.
• W2047810742 cites W2042772866 @default.
• W2047810742 cites W2043845638 @default.
• W2047810742 cites W2050328020 @default.
• W2047810742 cites W2050607994 @default.
• W2047810742 cites W2051872859 @default.
• W2047810742 cites W2057163861 @default.
• W2047810742 cites W2059711383 @default.
• W2047810742 cites W2070402931 @default.
• W2047810742 cites W2075761756 @default.
• W2047810742 cites W2076597255 @default.
• W2047810742 cites W2086000252 @default.
• W2047810742 cites W2093603344 @default.
• W2047810742 cites W2099445531 @default.
• W2047810742 cites W2106641477 @default.
• W2047810742 cites W2107277218 @default.
• W2047810742 cites W2108244474 @default.
• W2047810742 cites W2109925243 @default.
• W2047810742 cites W2116707460 @default.
• W2047810742 cites W2120382923 @default.
• W2047810742 cites W2122009877 @default.
• W2047810742 cites W2123029511 @default.
• W2047810742 cites W2126969627 @default.
• W2047810742 cites W2132632499 @default.
• W2047810742 cites W2151975923 @default.
• W2047810742 cites W2152609678 @default.
• W2047810742 cites W2155511376 @default.
• W2047810742 cites W2162405530 @default.
• W2047810742 cites W2163762391 @default.
• W2047810742 cites W2167619166 @default.
• W2047810742 cites W2168821725 @default.
• W2047810742 cites W2183044194 @default.
• W2047810742 cites W4234271761 @default.
• W2047810742 doi "https://doi.org/10.1016/j.ygcen.2011.11.031" @default.
• W2047810742 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22146795" @default.
• W2047810742 hasPublicationYear "2012" @default.
• W2047810742 type Work @default.
• W2047810742 sameAs 2047810742 @default.
• W2047810742 citedByCount "17" @default.
• W2047810742 countsByYear W20478107422012 @default.
• W2047810742 countsByYear W20478107422013 @default.
• W2047810742 countsByYear W20478107422015 @default.
• W2047810742 countsByYear W20478107422018 @default.
• W2047810742 countsByYear W20478107422021 @default.
• W2047810742 countsByYear W20478107422022 @default.
• W2047810742 countsByYear W20478107422023 @default.
• W2047810742 crossrefType "journal-article" @default.
• W2047810742 hasAuthorship W2047810742A5005183831 @default.
• W2047810742 hasAuthorship W2047810742A5008019045 @default.
• W2047810742 hasAuthorship W2047810742A5014627755 @default.
• W2047810742 hasAuthorship W2047810742A5020184311 @default.
• W2047810742 hasAuthorship W2047810742A5034232080 @default.
• W2047810742 hasConcept C104317684 @default.
• W2047810742 hasConcept C105580179 @default.
• W2047810742 hasConcept C126322002 @default.
• W2047810742 hasConcept C134018914 @default.
• W2047810742 hasConcept C150194340 @default.
• W2047810742 hasConcept C2777883778 @default.
• W2047810742 hasConcept C2778709874 @default.
• W2047810742 hasConcept C2779428213 @default.
• W2047810742 hasConcept C2780841215 @default.
• W2047810742 hasConcept C2909208804 @default.
• W2047810742 hasConcept C505870484 @default.
• W2047810742 hasConcept C54355233 @default.
• W2047810742 hasConcept C59493245 @default.
• W2047810742 hasConcept C71315377 @default.
• W2047810742 hasConcept C71924100 @default.
• W2047810742 hasConcept C86803240 @default.
• W2047810742 hasConceptScore W2047810742C104317684 @default.
• W2047810742 hasConceptScore W2047810742C105580179 @default.
• W2047810742 hasConceptScore W2047810742C126322002 @default.
• W2047810742 hasConceptScore W2047810742C134018914 @default.
• W2047810742 hasConceptScore W2047810742C150194340 @default.

• next