FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2047823507> ?p ?o ?g. }

• W2047823507 endingPage "7725" @default.
• W2047823507 startingPage "7719" @default.
• W2047823507 abstract "Privileged structure-based libraries have been shown to provide high affinity lead compounds for a variety of important biological targets. The present study describes the synthesis and screening of a 2-aminothiazole based compound library to determine their utility as antimicrobials, focusing on MRSA. Several of the compounds in this series demonstrated improved antimicrobial activity as compared to ceftriaxone (CTX), a β-lactam antibiotic. The most potent compound (21) had MICs in the range of 2-4 μg/ml across a panel of Staphylococcus aureus strains. In addition, trifluoromethoxy substituted aminothiazoles and aminobenzothiazoles were found to be potent antimicrobials with MICs of 2-16 μg/ml." @default.
• W2047823507 created "2016-06-24" @default.
• W2047823507 creator A5006147441 @default.
• W2047823507 creator A5016597383 @default.
• W2047823507 creator A5056534291 @default.
• W2047823507 creator A5075589850 @default.
• W2047823507 creator A5076533471 @default.
• W2047823507 creator A5088900927 @default.
• W2047823507 date "2012-12-01" @default.
• W2047823507 modified "2023-09-23" @default.
• W2047823507 title "Design and synthesis of 2-aminothiazole based antimicrobials targeting MRSA" @default.
• W2047823507 cites W1971581121 @default.
• W2047823507 cites W1978630931 @default.
• W2047823507 cites W2013193791 @default.
• W2047823507 cites W2013249162 @default.
• W2047823507 cites W2019578220 @default.
• W2047823507 cites W2039048061 @default.
• W2047823507 cites W2049431076 @default.
• W2047823507 cites W2055519077 @default.
• W2047823507 cites W2058002981 @default.
• W2047823507 cites W2086559602 @default.
• W2047823507 cites W2095025216 @default.
• W2047823507 cites W2118014593 @default.
• W2047823507 cites W2129847124 @default.
• W2047823507 cites W2139766660 @default.
• W2047823507 cites W2144261873 @default.
• W2047823507 cites W2162106505 @default.
• W2047823507 cites W2951322433 @default.
• W2047823507 cites W4235454029 @default.
• W2047823507 doi "https://doi.org/10.1016/j.bmcl.2012.09.095" @default.
• W2047823507 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23116888" @default.
• W2047823507 hasPublicationYear "2012" @default.
• W2047823507 type Work @default.
• W2047823507 sameAs 2047823507 @default.
• W2047823507 citedByCount "35" @default.
• W2047823507 countsByYear W20478235072013 @default.
• W2047823507 countsByYear W20478235072014 @default.
• W2047823507 countsByYear W20478235072015 @default.
• W2047823507 countsByYear W20478235072016 @default.
• W2047823507 countsByYear W20478235072017 @default.
• W2047823507 countsByYear W20478235072018 @default.
• W2047823507 countsByYear W20478235072019 @default.
• W2047823507 countsByYear W20478235072020 @default.
• W2047823507 countsByYear W20478235072022 @default.
• W2047823507 countsByYear W20478235072023 @default.
• W2047823507 crossrefType "journal-article" @default.
• W2047823507 hasAuthorship W2047823507A5006147441 @default.
• W2047823507 hasAuthorship W2047823507A5016597383 @default.
• W2047823507 hasAuthorship W2047823507A5056534291 @default.
• W2047823507 hasAuthorship W2047823507A5075589850 @default.
• W2047823507 hasAuthorship W2047823507A5076533471 @default.
• W2047823507 hasAuthorship W2047823507A5088900927 @default.
• W2047823507 hasConcept C178790620 @default.
• W2047823507 hasConcept C185592680 @default.
• W2047823507 hasConcept C21951064 @default.
• W2047823507 hasConcept C2776520383 @default.
• W2047823507 hasConcept C2779489039 @default.
• W2047823507 hasConcept C4937899 @default.
• W2047823507 hasConcept C501593827 @default.
• W2047823507 hasConcept C523546767 @default.
• W2047823507 hasConcept C54355233 @default.
• W2047823507 hasConcept C55493867 @default.
• W2047823507 hasConcept C71924100 @default.
• W2047823507 hasConcept C86803240 @default.
• W2047823507 hasConcept C89423630 @default.
• W2047823507 hasConcept C98274493 @default.
• W2047823507 hasConceptScore W2047823507C178790620 @default.
• W2047823507 hasConceptScore W2047823507C185592680 @default.
• W2047823507 hasConceptScore W2047823507C21951064 @default.
• W2047823507 hasConceptScore W2047823507C2776520383 @default.
• W2047823507 hasConceptScore W2047823507C2779489039 @default.
• W2047823507 hasConceptScore W2047823507C4937899 @default.
• W2047823507 hasConceptScore W2047823507C501593827 @default.
• W2047823507 hasConceptScore W2047823507C523546767 @default.
• W2047823507 hasConceptScore W2047823507C54355233 @default.
• W2047823507 hasConceptScore W2047823507C55493867 @default.
• W2047823507 hasConceptScore W2047823507C71924100 @default.
• W2047823507 hasConceptScore W2047823507C86803240 @default.
• W2047823507 hasConceptScore W2047823507C89423630 @default.
• W2047823507 hasConceptScore W2047823507C98274493 @default.
• W2047823507 hasIssue "24" @default.
• W2047823507 hasLocation W20478235071 @default.
• W2047823507 hasLocation W20478235072 @default.
• W2047823507 hasOpenAccess W2047823507 @default.
• W2047823507 hasPrimaryLocation W20478235071 @default.
• W2047823507 hasRelatedWork W1839011430 @default.
• W2047823507 hasRelatedWork W2036651554 @default.
• W2047823507 hasRelatedWork W2095212420 @default.
• W2047823507 hasRelatedWork W2326830576 @default.
• W2047823507 hasRelatedWork W2396822601 @default.
• W2047823507 hasRelatedWork W2753184995 @default.
• W2047823507 hasRelatedWork W2954159082 @default.
• W2047823507 hasRelatedWork W2978793169 @default.
• W2047823507 hasRelatedWork W3125557516 @default.
• W2047823507 hasRelatedWork W2894777053 @default.
• W2047823507 hasVolume "22" @default.
• W2047823507 isParatext "false" @default.
• W2047823507 isRetracted "false" @default.

• next