Matches in SemOpenAlex for { <https://semopenalex.org/work/W2047845758> ?p ?o ?g. }
- W2047845758 endingPage "7764" @default.
- W2047845758 startingPage "7759" @default.
- W2047845758 abstract "Double-strand breaks (DSBs) are intermediates in several physiological processes including V(D)J and class switch recombination. They are also potent substrates for chromosomal translocations that arise as by-products of antigen receptor gene assembly in lymphocytes. ATM is one among several key proteins involved in the detection, signaling and repair of DNA breaks. Despite redundancies in DSB signaling pathways, it has recently been demonstrated that ATM deficient lymphocytes can survive and proliferate several generations in vitro and in vivo despite harboring terminally deleted chromosomes produced by V(D)J recombination. In this review, we discuss how two complementary genome maintenance functions mediated by ATM prevent lymphocytes from adapting to persistent DNA damage." @default.
- W2047845758 created "2016-06-24" @default.
- W2047845758 creator A5003699560 @default.
- W2047845758 creator A5028769361 @default.
- W2047845758 creator A5032791775 @default.
- W2047845758 date "2007-12-10" @default.
- W2047845758 modified "2023-10-17" @default.
- W2047845758 title "Breaking down cell cycle checkpoints and DNA repair during antigen receptor gene assembly" @default.
- W2047845758 cites W129919879 @default.
- W2047845758 cites W1966200086 @default.
- W2047845758 cites W1967825549 @default.
- W2047845758 cites W1969237880 @default.
- W2047845758 cites W1975776530 @default.
- W2047845758 cites W1978177909 @default.
- W2047845758 cites W1980725176 @default.
- W2047845758 cites W1988821953 @default.
- W2047845758 cites W1992783373 @default.
- W2047845758 cites W2011799603 @default.
- W2047845758 cites W2015125731 @default.
- W2047845758 cites W2015414930 @default.
- W2047845758 cites W2018458310 @default.
- W2047845758 cites W2019219567 @default.
- W2047845758 cites W2024442567 @default.
- W2047845758 cites W2027083790 @default.
- W2047845758 cites W2031292590 @default.
- W2047845758 cites W2034884571 @default.
- W2047845758 cites W2036339686 @default.
- W2047845758 cites W2039704215 @default.
- W2047845758 cites W2041122142 @default.
- W2047845758 cites W2044958508 @default.
- W2047845758 cites W2048729396 @default.
- W2047845758 cites W2051639914 @default.
- W2047845758 cites W2053844006 @default.
- W2047845758 cites W2059347700 @default.
- W2047845758 cites W2059574913 @default.
- W2047845758 cites W2061053923 @default.
- W2047845758 cites W2062284662 @default.
- W2047845758 cites W2065369524 @default.
- W2047845758 cites W2071182326 @default.
- W2047845758 cites W2073896350 @default.
- W2047845758 cites W2079466993 @default.
- W2047845758 cites W2079725260 @default.
- W2047845758 cites W2084745121 @default.
- W2047845758 cites W2092375438 @default.
- W2047845758 cites W2098238130 @default.
- W2047845758 cites W2101222641 @default.
- W2047845758 cites W2103489555 @default.
- W2047845758 cites W2104973497 @default.
- W2047845758 cites W2106336456 @default.
- W2047845758 cites W2108547322 @default.
- W2047845758 cites W2110394056 @default.
- W2047845758 cites W2113574608 @default.
- W2047845758 cites W2113603158 @default.
- W2047845758 cites W2114983967 @default.
- W2047845758 cites W2131761459 @default.
- W2047845758 cites W2133291090 @default.
- W2047845758 cites W2146917785 @default.
- W2047845758 cites W2149468013 @default.
- W2047845758 cites W2152456839 @default.
- W2047845758 cites W2158691993 @default.
- W2047845758 cites W2167333291 @default.
- W2047845758 cites W4240635914 @default.
- W2047845758 cites W4381307530 @default.
- W2047845758 cites W62878709 @default.
- W2047845758 cites W99705021 @default.
- W2047845758 doi "https://doi.org/10.1038/sj.onc.1210873" @default.
- W2047845758 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18066088" @default.
- W2047845758 hasPublicationYear "2007" @default.
- W2047845758 type Work @default.
- W2047845758 sameAs 2047845758 @default.
- W2047845758 citedByCount "22" @default.
- W2047845758 countsByYear W20478457582012 @default.
- W2047845758 countsByYear W20478457582013 @default.
- W2047845758 countsByYear W20478457582014 @default.
- W2047845758 countsByYear W20478457582016 @default.
- W2047845758 countsByYear W20478457582018 @default.
- W2047845758 countsByYear W20478457582023 @default.
- W2047845758 crossrefType "journal-article" @default.
- W2047845758 hasAuthorship W2047845758A5003699560 @default.
- W2047845758 hasAuthorship W2047845758A5028769361 @default.
- W2047845758 hasAuthorship W2047845758A5032791775 @default.
- W2047845758 hasBestOaLocation W20478457581 @default.
- W2047845758 hasConcept C104317684 @default.
- W2047845758 hasConcept C134935766 @default.
- W2047845758 hasConcept C143425029 @default.
- W2047845758 hasConcept C156695909 @default.
- W2047845758 hasConcept C2780254951 @default.
- W2047845758 hasConcept C54355233 @default.
- W2047845758 hasConcept C552990157 @default.
- W2047845758 hasConcept C86803240 @default.
- W2047845758 hasConcept C95444343 @default.
- W2047845758 hasConceptScore W2047845758C104317684 @default.
- W2047845758 hasConceptScore W2047845758C134935766 @default.
- W2047845758 hasConceptScore W2047845758C143425029 @default.
- W2047845758 hasConceptScore W2047845758C156695909 @default.
- W2047845758 hasConceptScore W2047845758C2780254951 @default.
- W2047845758 hasConceptScore W2047845758C54355233 @default.
- W2047845758 hasConceptScore W2047845758C552990157 @default.