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- W2047854511 abstract "In an attempt to develop an appropriate infusion program in a continuous subcutaneous insulin infusion system, a conventional pharmacodynamic model (the Bolie model) for describing the relationship between blood glucose and serum insulin levels was evaluated, using a depancreatized dog preparation. The Bolie model was found useful in estimating the basal insulin infusion rate. However, the model could not predict the serum insulin concentration-time profile required to maintain the postprandial blood glucose levels within a physiological range. It will be necessary to develop a more appropriate model for determining the prandial subcutaneous insulin infusion rates in the continuous subcutaneous insulin infusion system." @default.
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- W2047854511 date "1985-01-01" @default.
- W2047854511 modified "2023-09-26" @default.
- W2047854511 title "Evaluation of the Bolie model describing blood glucose response for the application to continuous subcutaneous insulin infusion." @default.
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- W2047854511 doi "https://doi.org/10.1248/bpb1978.8.808" @default.
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