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- W2047921026 abstract "Aggregation-caused signal change is a well-established mechanism by now and has been widely used as the basis for optical probe and sensor development. Compared to aggregation, its reverse process, disaggregation, has received much less attention and is not properly discussed in the literature so far. With the less established paradigm or mechanism, although some of the reported sensors and probes seem to work through disaggregation phenomena, the proper interpretation of the results and applying the concept to novel probe development is seriously hampered. The process from aggregation to disaggregation generally causes a recovery or enhancement of fluorescence signals, and thus provides an interesting new path to design turn-on probes. This tutorial review will provide the balanced comparison between aggregation and disaggregation mechanism, and focuses on the less explored advantages of disaggregation as a novel sensing mechanism and its recent applications in probe development." @default.
- W2047921026 created "2016-06-24" @default.
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- W2047921026 date "2014-01-01" @default.
- W2047921026 modified "2023-09-30" @default.
- W2047921026 title "The role of “disaggregation” in optical probe development" @default.
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- W2047921026 doi "https://doi.org/10.1039/c3cs60368g" @default.
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