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- W2047970619 abstract "Thirty-one patients with disseminated melanoma or renal cell cancer (RCC) who had a limited relapse or persistent disease after a partial or complete response to interleukin-2 (IL-2)-based immunotherapy underwent resection of progressing tumors or residual sites of disease. There were no surgery-related deaths. The median time to disease progression after resection for patients with RCC (n = 16) and melanoma (n = 15) was 11 and 5 months, respectively. All patients with melanoma had tumor progression within 10 months of surgery. Seven of 16 patients with RCC were free of tumor progression 4 to 44 months after surgery. Three of 12 patients with RCC rendered disease-free by surgery remain disease-free after 2 years. These data suggest that surgical resection is a reasonable option in selected patients who have a relapse after responding to IL-2-based immunotherapy. Although this retrospective study could not determine the relative survival benefits of surgery and immunotherapy, it showed that resection of metastatic disease after a response to immunotherapy can result in significant disease-free survival in patients with RCC but not melanoma." @default.
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- W2047970619 date "1992-04-01" @default.
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- W2047970619 title "Surgical resection of metastatic renal cell carcinoma and melanoma after response to interleukin-2-based immunotherapy" @default.
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- W2047970619 doi "https://doi.org/10.1002/1097-0142(19920401)69:7<1850::aid-cncr2820690729>3.0.co;2-i" @default.
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