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- W2047987250 abstract "It is common practice to give an anticholinergic drug during barium enema examination when it is difficult to fill the colon because of spasm, incontinence or some other reason. In 1958 Welin recommended the routine use of atropine by mouth 30 minutes before the examination in order to reduce mucus secretion and alleviate the discomfort of the examination. Another more powerful anticholinergic drug, propantheline bromide (ProBanthine) was a common favourite for the relief of colonic spasm (Ferrucci and Benedict, 1971), but side effects proved troublesome. Dilatation of the pupils with loss of accommodating power causing blurred vision is common, often lasting for several hours and sometimes for as long as one to three days. For this reason hyoscine butylbromide (Buscopan) has become more popular, because prolonged blurring of vision is rare and other side effects are less of a problem. There is also a risk of precipitating glaucoma with these drugs, but one is only likely to run into trouble in patients prone to episodes of closed angle glaucoma. Symptoms of this condition are painful attacks of blurred vision, accompanied by haloes around lights. The effects of hyoscine may be enhanced by concomitant administration of other drugs with parasympatholytic properties, such as some antihistamines, phenothiazines and the tricyclic antidepressants." @default.
- W2047987250 created "2016-06-24" @default.
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- W2047987250 date "1976-04-01" @default.
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- W2047987250 title "Radiology now. The colon pacified" @default.
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- W2047987250 doi "https://doi.org/10.1259/0007-1285-49-580-303" @default.
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