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- W2048049507 abstract "Abstract Three N -diazoacetylglycine derivatives and two N -diazoacetylglycylglycine derivatives were examined for their differential effects on subcutaneous tumor growth and lung metastasis formation in mice bearing Lewis lung carcinoma. None of the tested compounds caused marked inhibition of primary tumor growth, even at maximum tolerated dosages. However, the two N -diazoacetylglycine and N -diazoacetylglycylglycine amide derivatives respectively caused a dramatic and a moderate inhibition of lung metastasis formation. The lack of correlation between inhibition of subcutaneous tumor growth and formation of lung secondaries indicates that the two amide derivatives possess selective antimetastatic properties." @default.
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- W2048049507 date "1979-04-01" @default.
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- W2048049507 title "Selective antimetastatic effects of N-diazoacetylglycine derivatives in mice" @default.
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- W2048049507 doi "https://doi.org/10.1016/0014-2964(79)90098-7" @default.
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