Matches in SemOpenAlex for { <https://semopenalex.org/work/W2048051196> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2048051196 endingPage "1127" @default.
- W2048051196 startingPage "1119" @default.
- W2048051196 abstract "1. Treatment of isolated rat liver mitochondria with methyl methacrylate (MM) produced membrane disruption as evidenced by the release of citrate synthase, and changes in the ultrastructure of mitochondria. 2. At concentration 0.1%, MM uncoupled oxidative phosphorylation as evidenced by stimulation of state 4 respiration supported either by pyruvate plus malate or succinate (+rotenone) and ATP-ase activity in intact mitochondria. 3. At concentration 1% MM stimulated ATP-ase activity in intact mitochondria and succinate (+rotenone) oxidation at state 4 and was without effect on this substrate oxidation at state 3. 4. MM inhibited pyruvate plus malate oxidation either at state 3 or in the presence of uncoupling agents. 5. MM inhibited the NADH oxidase of electron transport particles at a concentration which failed to inhibit either succinic oxidase or the NADH-ferricyanide reductase activity. 6. The data presented suggest that in the isolated mitochondria MM inhibits NADH oxidation in the vicinity of the rotenone sensitive site of complex I. 7. The general conclusion is that MM may block an electron transport and to uncouple oxidative phosphorylation in rat liver mitochondria. The overall in vitro effect would be to prevent ATP synthesis which could result in cell death under in vivo conditions." @default.
- W2048051196 created "2016-06-24" @default.
- W2048051196 creator A5026372634 @default.
- W2048051196 date "1994-09-01" @default.
- W2048051196 modified "2023-10-12" @default.
- W2048051196 title "Effect of methyl methacrylate on mitochondrial function and structure" @default.
- W2048051196 cites W1537460658 @default.
- W2048051196 cites W1588942290 @default.
- W2048051196 cites W1890683428 @default.
- W2048051196 cites W1965162539 @default.
- W2048051196 cites W1970441640 @default.
- W2048051196 cites W1975183707 @default.
- W2048051196 cites W2037046025 @default.
- W2048051196 cites W2049331371 @default.
- W2048051196 cites W2064696471 @default.
- W2048051196 cites W2075046972 @default.
- W2048051196 cites W2089402680 @default.
- W2048051196 cites W2094289342 @default.
- W2048051196 cites W2161352961 @default.
- W2048051196 cites W2254196916 @default.
- W2048051196 cites W2291903346 @default.
- W2048051196 cites W2465212593 @default.
- W2048051196 cites W954944586 @default.
- W2048051196 doi "https://doi.org/10.1016/0020-711x(94)90134-1" @default.
- W2048051196 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7988736" @default.
- W2048051196 hasPublicationYear "1994" @default.
- W2048051196 type Work @default.
- W2048051196 sameAs 2048051196 @default.
- W2048051196 citedByCount "21" @default.
- W2048051196 countsByYear W20480511962012 @default.
- W2048051196 countsByYear W20480511962015 @default.
- W2048051196 countsByYear W20480511962016 @default.
- W2048051196 countsByYear W20480511962019 @default.
- W2048051196 countsByYear W20480511962022 @default.
- W2048051196 countsByYear W20480511962023 @default.
- W2048051196 crossrefType "journal-article" @default.
- W2048051196 hasAuthorship W2048051196A5026372634 @default.
- W2048051196 hasConcept C112243037 @default.
- W2048051196 hasConcept C123249941 @default.
- W2048051196 hasConcept C181199279 @default.
- W2048051196 hasConcept C185592680 @default.
- W2048051196 hasConcept C24840226 @default.
- W2048051196 hasConcept C2777411777 @default.
- W2048051196 hasConcept C2778389096 @default.
- W2048051196 hasConcept C2779564974 @default.
- W2048051196 hasConcept C2779965811 @default.
- W2048051196 hasConcept C28859421 @default.
- W2048051196 hasConcept C55493867 @default.
- W2048051196 hasConcept C57600042 @default.
- W2048051196 hasConcept C86803240 @default.
- W2048051196 hasConceptScore W2048051196C112243037 @default.
- W2048051196 hasConceptScore W2048051196C123249941 @default.
- W2048051196 hasConceptScore W2048051196C181199279 @default.
- W2048051196 hasConceptScore W2048051196C185592680 @default.
- W2048051196 hasConceptScore W2048051196C24840226 @default.
- W2048051196 hasConceptScore W2048051196C2777411777 @default.
- W2048051196 hasConceptScore W2048051196C2778389096 @default.
- W2048051196 hasConceptScore W2048051196C2779564974 @default.
- W2048051196 hasConceptScore W2048051196C2779965811 @default.
- W2048051196 hasConceptScore W2048051196C28859421 @default.
- W2048051196 hasConceptScore W2048051196C55493867 @default.
- W2048051196 hasConceptScore W2048051196C57600042 @default.
- W2048051196 hasConceptScore W2048051196C86803240 @default.
- W2048051196 hasIssue "9" @default.
- W2048051196 hasLocation W20480511961 @default.
- W2048051196 hasLocation W20480511962 @default.
- W2048051196 hasOpenAccess W2048051196 @default.
- W2048051196 hasPrimaryLocation W20480511961 @default.
- W2048051196 hasRelatedWork W1972221736 @default.
- W2048051196 hasRelatedWork W2025667834 @default.
- W2048051196 hasRelatedWork W2048051196 @default.
- W2048051196 hasRelatedWork W2074527668 @default.
- W2048051196 hasRelatedWork W2077383445 @default.
- W2048051196 hasRelatedWork W2085832188 @default.
- W2048051196 hasRelatedWork W2131629779 @default.
- W2048051196 hasRelatedWork W2153407827 @default.
- W2048051196 hasRelatedWork W2223865021 @default.
- W2048051196 hasRelatedWork W4220997172 @default.
- W2048051196 hasVolume "26" @default.
- W2048051196 isParatext "false" @default.
- W2048051196 isRetracted "false" @default.
- W2048051196 magId "2048051196" @default.
- W2048051196 workType "article" @default.