FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2048081129> ?p ?o ?g. }

• W2048081129 endingPage "910" @default.
• W2048081129 startingPage "907" @default.
• W2048081129 abstract "BACKGROUND Claudins are a family of approximately 23 integral membrane tight junction (TJ) proteins that maintain cell polarity and paracellular barrier functions in epithelial and endothelial cells. Although Claudin-1 was demonstrated to be typically downregulated in various cancers, the precise expression patterns of this protein in normal and neoplastic tissues remain poorly characterized. METHODS Using immunohistochemistry, the expression of Claudin-1 was investigated in prostate tissue samples arranged in a tissue microarray (TMA) format and comprising elements of normal prostatic epithelium (n = 6), benign prostatic hyperplasia (BPH; n = 38), prostatic intraepithelial neoplasia (PIN; n = 11), and prostate adenocarcinoma (n = 48). The Claudin-1 expression pattern was compared with that of the basal cell-specific markers, p63, and HMW cytokeratin (34βE12), by employing double-labeling techniques in conjunction with image analysis methods utilizing color deconvolution algorithms. RESULTS In benign prostatic epithelium, pronounced Claudin-1 expression was observed in the basal cell layer with no staining in luminal cells. Prostate adenocarcinoma specimens from 98% (47/48) patients lacked Claudin-1 immunostaining, and no cases contained >5% immunopositive tumor cells. CONCLUSIONS Claudin-1 immunohistochemistry should be considered for use as a new diagnostic tool for distinguishing malignant from benign lesions of the prostate. Prostate 67: 907–910, 2007. © 2007 Wiley-Liss, Inc." @default.
• W2048081129 created "2016-06-24" @default.
• W2048081129 creator A5043823149 @default.
• W2048081129 creator A5059438505 @default.
• W2048081129 creator A5061465705 @default.
• W2048081129 creator A5072504891 @default.
• W2048081129 creator A5088290549 @default.
• W2048081129 date "2007-01-01" @default.
• W2048081129 modified "2023-09-24" @default.
• W2048081129 title "Claudin-1 immunohistochemistry for distinguishing malignant from benign epithelial lesions of prostate" @default.
• W2048081129 cites W1926327739 @default.
• W2048081129 cites W1985136204 @default.
• W2048081129 cites W2024487262 @default.
• W2048081129 cites W2026761074 @default.
• W2048081129 cites W2030349812 @default.
• W2048081129 cites W2038863582 @default.
• W2048081129 cites W2079482620 @default.
• W2048081129 cites W2100269253 @default.
• W2048081129 cites W2101929583 @default.
• W2048081129 cites W2140600628 @default.
• W2048081129 cites W2148888894 @default.
• W2048081129 cites W2168220121 @default.
• W2048081129 cites W2170505336 @default.
• W2048081129 doi "https://doi.org/10.1002/pros.20578" @default.
• W2048081129 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17440968" @default.
• W2048081129 hasPublicationYear "2007" @default.
• W2048081129 type Work @default.
• W2048081129 sameAs 2048081129 @default.
• W2048081129 citedByCount "26" @default.
• W2048081129 countsByYear W20480811292013 @default.
• W2048081129 countsByYear W20480811292014 @default.
• W2048081129 countsByYear W20480811292015 @default.
• W2048081129 countsByYear W20480811292016 @default.
• W2048081129 countsByYear W20480811292019 @default.
• W2048081129 countsByYear W20480811292020 @default.
• W2048081129 countsByYear W20480811292021 @default.
• W2048081129 countsByYear W20480811292022 @default.
• W2048081129 crossrefType "journal-article" @default.
• W2048081129 hasAuthorship W2048081129A5043823149 @default.
• W2048081129 hasAuthorship W2048081129A5059438505 @default.
• W2048081129 hasAuthorship W2048081129A5061465705 @default.
• W2048081129 hasAuthorship W2048081129A5072504891 @default.
• W2048081129 hasAuthorship W2048081129A5088290549 @default.
• W2048081129 hasConcept C121608353 @default.
• W2048081129 hasConcept C126322002 @default.
• W2048081129 hasConcept C142724271 @default.
• W2048081129 hasConcept C177779419 @default.
• W2048081129 hasConcept C193270364 @default.
• W2048081129 hasConcept C204232928 @default.
• W2048081129 hasConcept C2776235491 @default.
• W2048081129 hasConcept C2777562237 @default.
• W2048081129 hasConcept C2779012181 @default.
• W2048081129 hasConcept C2779534503 @default.
• W2048081129 hasConcept C2780192828 @default.
• W2048081129 hasConcept C2781182431 @default.
• W2048081129 hasConcept C4224716 @default.
• W2048081129 hasConcept C51872919 @default.
• W2048081129 hasConcept C529295009 @default.
• W2048081129 hasConcept C71924100 @default.
• W2048081129 hasConcept C86803240 @default.
• W2048081129 hasConcept C95444343 @default.
• W2048081129 hasConceptScore W2048081129C121608353 @default.
• W2048081129 hasConceptScore W2048081129C126322002 @default.
• W2048081129 hasConceptScore W2048081129C142724271 @default.
• W2048081129 hasConceptScore W2048081129C177779419 @default.
• W2048081129 hasConceptScore W2048081129C193270364 @default.
• W2048081129 hasConceptScore W2048081129C204232928 @default.
• W2048081129 hasConceptScore W2048081129C2776235491 @default.
• W2048081129 hasConceptScore W2048081129C2777562237 @default.
• W2048081129 hasConceptScore W2048081129C2779012181 @default.
• W2048081129 hasConceptScore W2048081129C2779534503 @default.
• W2048081129 hasConceptScore W2048081129C2780192828 @default.
• W2048081129 hasConceptScore W2048081129C2781182431 @default.
• W2048081129 hasConceptScore W2048081129C4224716 @default.
• W2048081129 hasConceptScore W2048081129C51872919 @default.
• W2048081129 hasConceptScore W2048081129C529295009 @default.
• W2048081129 hasConceptScore W2048081129C71924100 @default.
• W2048081129 hasConceptScore W2048081129C86803240 @default.
• W2048081129 hasConceptScore W2048081129C95444343 @default.
• W2048081129 hasIssue "9" @default.
• W2048081129 hasLocation W20480811291 @default.
• W2048081129 hasLocation W20480811292 @default.
• W2048081129 hasOpenAccess W2048081129 @default.
• W2048081129 hasPrimaryLocation W20480811291 @default.
• W2048081129 hasRelatedWork W1991840061 @default.
• W2048081129 hasRelatedWork W202920663 @default.
• W2048081129 hasRelatedWork W2048081129 @default.
• W2048081129 hasRelatedWork W2083967664 @default.
• W2048081129 hasRelatedWork W2088783977 @default.
• W2048081129 hasRelatedWork W2114566138 @default.
• W2048081129 hasRelatedWork W2346103388 @default.
• W2048081129 hasRelatedWork W2350150832 @default.
• W2048081129 hasRelatedWork W2396349469 @default.
• W2048081129 hasRelatedWork W3092363934 @default.
• W2048081129 hasVolume "67" @default.
• W2048081129 isParatext "false" @default.
• W2048081129 isRetracted "false" @default.
• W2048081129 magId "2048081129" @default.

• next