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- W2048083555 abstract "It was found that ATP and cyclic AMP were greatly increased in human blood lymphocytes which were deficient in ADA. Certain other purine and pyrimidine nucleotides were elevated but to a lesser degree. Energy production in these cells may be inhibited by the increase in nucleotides since the ATP:ADP ratio was significantly below normal. Thus it appears that the immunologic deficiency in human ADA deficiency is related to increased nucleotide concentrations in the lymphocytes." @default.
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- W2048083555 date "1977-07-01" @default.
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- W2048083555 title "Increased purine nucleotides in adenosinedeaminase-deficient lymphocytes" @default.
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- W2048083555 doi "https://doi.org/10.1016/s0022-3476(77)80442-3" @default.
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