Matches in SemOpenAlex for { <https://semopenalex.org/work/W2048097051> ?p ?o ?g. }
Showing items 1 to 62 of
62
with 100 items per page.
- W2048097051 endingPage "480" @default.
- W2048097051 startingPage "476" @default.
- W2048097051 abstract "Rat pineal thyroxine 5'-deiodinase (5'-D) activity was detectable by 5 days after birth. Nyctohemeral differences became significant by 10 days of age and gradually reached adult magnitude at 1-2 months, primarily due to a progressive increase in nocturnal enzyme activity. A nyctohemeral difference in N-acetyltransferase (NAT) activity was observed by 5 days postnatally and the maturation of NAT rhythmicity was characterized by both a decrease in diurnal and an increase in nocturnal enzyme activity. The maturation of 5'-D rhythmicity was slower than that of NAT. Isoproterenol stimulated 5'-D activity in 5-day-old rats in which there was no spontaneous nyctohemeral 5'-D rhythm, suggesting that the appearance of rhythmicity in pineal 5'-D may depend on the development of pineal innervation. Melatonin was detectable in plasma by 5 days postnatally and reached adult levels at 21 days. A nyctohemeral difference in plasma melatonin concentration existed from day 5 with the highest value at midnight. The difference between noon and midnight increased approximately 10-fold to the adult amplitude by 15 days of age. There was a transient rise of both diurnal and nocturnal plasma melatonin concentration which peaked at 10 days before dropping severalfold to the adult level for both noon and midnight values by 21 days. Since the rhythms of pineal NAT activity and of plasma melatonin concentration are established before that of pineal 5'-D, it is unlikely that the rhythm of melatonin secretion is initiated by a prior maturation of the pineal 5'-D rhythm." @default.
- W2048097051 created "2016-06-24" @default.
- W2048097051 creator A5013650206 @default.
- W2048097051 creator A5014100032 @default.
- W2048097051 creator A5026423669 @default.
- W2048097051 creator A5049106742 @default.
- W2048097051 creator A5085828129 @default.
- W2048097051 date "1989-01-01" @default.
- W2048097051 modified "2023-09-28" @default.
- W2048097051 title "Ontogenesis of Pineal Thyroxine 5’-Deiodinase Activity and Plasma Melatonin Concentration in the Rat" @default.
- W2048097051 doi "https://doi.org/10.1159/000125266" @default.
- W2048097051 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2812278" @default.
- W2048097051 hasPublicationYear "1989" @default.
- W2048097051 type Work @default.
- W2048097051 sameAs 2048097051 @default.
- W2048097051 citedByCount "10" @default.
- W2048097051 crossrefType "journal-article" @default.
- W2048097051 hasAuthorship W2048097051A5013650206 @default.
- W2048097051 hasAuthorship W2048097051A5014100032 @default.
- W2048097051 hasAuthorship W2048097051A5026423669 @default.
- W2048097051 hasAuthorship W2048097051A5049106742 @default.
- W2048097051 hasAuthorship W2048097051A5085828129 @default.
- W2048097051 hasConcept C121446783 @default.
- W2048097051 hasConcept C126322002 @default.
- W2048097051 hasConcept C134018914 @default.
- W2048097051 hasConcept C135343436 @default.
- W2048097051 hasConcept C2777334680 @default.
- W2048097051 hasConcept C2778182776 @default.
- W2048097051 hasConcept C2780059843 @default.
- W2048097051 hasConcept C71924100 @default.
- W2048097051 hasConcept C86803240 @default.
- W2048097051 hasConceptScore W2048097051C121446783 @default.
- W2048097051 hasConceptScore W2048097051C126322002 @default.
- W2048097051 hasConceptScore W2048097051C134018914 @default.
- W2048097051 hasConceptScore W2048097051C135343436 @default.
- W2048097051 hasConceptScore W2048097051C2777334680 @default.
- W2048097051 hasConceptScore W2048097051C2778182776 @default.
- W2048097051 hasConceptScore W2048097051C2780059843 @default.
- W2048097051 hasConceptScore W2048097051C71924100 @default.
- W2048097051 hasConceptScore W2048097051C86803240 @default.
- W2048097051 hasIssue "4" @default.
- W2048097051 hasLocation W20480970511 @default.
- W2048097051 hasLocation W20480970512 @default.
- W2048097051 hasOpenAccess W2048097051 @default.
- W2048097051 hasPrimaryLocation W20480970511 @default.
- W2048097051 hasRelatedWork W1972126140 @default.
- W2048097051 hasRelatedWork W1980207544 @default.
- W2048097051 hasRelatedWork W2009692691 @default.
- W2048097051 hasRelatedWork W2017830665 @default.
- W2048097051 hasRelatedWork W2050416457 @default.
- W2048097051 hasRelatedWork W2075463443 @default.
- W2048097051 hasRelatedWork W2090338064 @default.
- W2048097051 hasRelatedWork W2092341993 @default.
- W2048097051 hasRelatedWork W2133675714 @default.
- W2048097051 hasRelatedWork W2797587270 @default.
- W2048097051 hasVolume "50" @default.
- W2048097051 isParatext "false" @default.
- W2048097051 isRetracted "false" @default.
- W2048097051 magId "2048097051" @default.
- W2048097051 workType "article" @default.