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- W2048138867 abstract "Letters15 July 1993Treatment of Myxedema-Associated Cardiogenic ShockIrwin Klein, MDIrwin Klein, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-119-2-199307150-00016 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:MacKerrow and colleagues [1] reported on the ability of triiodothyronine to treat cardiogenic shock resulting from severe hypothyroidism (myxedema); however, certain points must be clarified.First, the authors conclude that their patient had Sheehan syndrome because she was unable to lactate after her last pregnancy. In the absence of significant hemorrhage or obstetrical trauma, an equally likely diagnosis would be lymphocytic hypophysitis [2], which would account for secondary adrenal and thyroid failure.That the patient failed to improve and, in fact, worsened over the first 5 days while receiving therapy with oral l-thyroxine, 50 g/d, is not ...References1. MacKerrow SD, Osborn LA, Levy H, Eaton RP, Economou P. Myxedema-associated cardiogenic shock treated with intravenous triiodothyronine. Ann Intern Med. 1992; 117:1014-5. Google Scholar2. Portocarrero CJ, Robinson AG, Taylor AJ, Klein I. Lymphoid hypophysistis: an unusual cause of hyperprolactinemia and enlarged sella turcica. J Am Med Assoc. 1981; 246:1811-3. Google Scholar3. Klein I. Thyroid hormone and high blood pressure. In: Laragh JH, Brenner BM, Kaplan NM, eds. Endocrine Mechanisms in Hypertension. v. 2. New York: Raven Press; 1989:61-80. Google Scholar4. Ojamaa K, Balkman C, Klein I. Acute effects of T3 on arterial smooth muscle cells. Ann Thorac Surg. 1993; (In press). Google Scholar5. Klein I. Thyroid hormone and the cardiovascular system. Am J Med. 1990; 88:642-7. Google Scholar Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 15 July 1993Volume 119, Issue 2Page: 168-169KeywordsHypothyroidismLactatesPregnancyShockSmooth muscle cellsSystemic vascular resistanceThyroidThyroid hormonesThyroxineTriiodothyronine Issue Published: 15 July 1993 Copyright & PermissionsCopyright © 1993 by American College of Physicians. All Rights Reserved.PDF downloadLoading ..." @default.
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- W2048138867 title "Treatment of Myxedema-Associated Cardiogenic Shock" @default.
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