FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2048142893> ?p ?o ?g. }

• W2048142893 endingPage "c2697" @default.
• W2048142893 startingPage "c2697" @default.
• W2048142893 abstract "<b>Objectives</b> To determine the incidence and characteristics of randomised controlled trials that report using the modified intention to treat approach, and how the approach is described. <b>Design</b> Systematic review. <b>Data sources</b> PubMed, Embase, Cochrane central register of controlled trials, ISI Web of Knowledge, Ovid, HighWire Press, Science-Direct, Ingenta, Medscape, BioMed Central, Springer, and Wiley, from inception to December 2006. <b>Main outcome measures</b> Incidence of trials in which use of modified intention to treat was reported, and how the approach was described (classified according to the type and number of deviations from the intention to treat approach). <b>Results</b> 475 randomised controlled trials reported use of a modified intention to treat analysis. Of these, 76 (16%) were published in five highly cited general medical journals. The incidence of all trials that reported use of modified intention to treat published in journals indexed in Medline increased from 0.006% in 1982-6 to 0.5% in 2002-6 (P<0.001 for linear trend). When the description of the modified intention to treat was examined in each trial, 192 (40%) reported one type of deviation from the intention to treat approach, 261 (55%) reported two or more types, and 22 (5%) did not describe any type. In 266 (56%) of the trials the deviation was related to the treatment received, in 196 (41%) to a post baseline assessment, in 118 (25%) to a baseline assessment, in 108 (23%) to a target condition, and in 23 (5%) to follow-up. Post-randomisation exclusions occurred in 380 (80%) trials. The results reported by 270 of the 352 (77%) superiority trials favoured the drug under investigation. All of the 123 trials using equivalence or non-inferiority methods to investigate interventions reported results that favoured their assumptions. <b>Conclusions</b> Randomised controlled trials that report using a modified intention to treat are increasingly being published in the medical literature. The descriptions of such an approach were ambiguous, and may cover any type of descriptions for exclusion, such as missing data and deviation from protocol. Explicit statements about post-randomisation exclusions should replace the ambiguous terminology of modified intention to treat." @default.
• W2048142893 created "2016-06-24" @default.
• W2048142893 creator A5062422288 @default.
• W2048142893 creator A5071961044 @default.
• W2048142893 date "2010-06-14" @default.
• W2048142893 modified "2023-10-14" @default.
• W2048142893 title "Modified intention to treat reporting in randomised controlled trials: systematic review" @default.
• W2048142893 cites W1259290134 @default.
• W2048142893 cites W1529485074 @default.
• W2048142893 cites W155746043 @default.
• W2048142893 cites W1663134060 @default.
• W2048142893 cites W197059223 @default.
• W2048142893 cites W1984052453 @default.
• W2048142893 cites W1986360186 @default.
• W2048142893 cites W1987186637 @default.
• W2048142893 cites W1993417604 @default.
• W2048142893 cites W2000522086 @default.
• W2048142893 cites W2002583647 @default.
• W2048142893 cites W2004742822 @default.
• W2048142893 cites W2006780292 @default.
• W2048142893 cites W2007239126 @default.
• W2048142893 cites W2014638066 @default.
• W2048142893 cites W2038361874 @default.
• W2048142893 cites W2044763202 @default.
• W2048142893 cites W2049321668 @default.
• W2048142893 cites W2057810715 @default.
• W2048142893 cites W2060584773 @default.
• W2048142893 cites W2061717662 @default.
• W2048142893 cites W2074736802 @default.
• W2048142893 cites W2076682535 @default.
• W2048142893 cites W2090648579 @default.
• W2048142893 cites W2097394217 @default.
• W2048142893 cites W2105662053 @default.
• W2048142893 cites W2106051200 @default.
• W2048142893 cites W2115176304 @default.
• W2048142893 cites W2116783571 @default.
• W2048142893 cites W2123275168 @default.
• W2048142893 cites W2132731224 @default.
• W2048142893 cites W2133774931 @default.
• W2048142893 cites W2134861067 @default.
• W2048142893 cites W2137745476 @default.
• W2048142893 cites W2142081149 @default.
• W2048142893 cites W2147581820 @default.
• W2048142893 cites W2155839539 @default.
• W2048142893 cites W2159096825 @default.
• W2048142893 cites W2160152341 @default.
• W2048142893 cites W2162036437 @default.
• W2048142893 cites W2326799365 @default.
• W2048142893 cites W4300481656 @default.
• W2048142893 doi "https://doi.org/10.1136/bmj.c2697" @default.
• W2048142893 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2885592" @default.
• W2048142893 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20547685" @default.
• W2048142893 hasPublicationYear "2010" @default.
• W2048142893 type Work @default.
• W2048142893 sameAs 2048142893 @default.
• W2048142893 citedByCount "166" @default.
• W2048142893 countsByYear W20481428932012 @default.
• W2048142893 countsByYear W20481428932013 @default.
• W2048142893 countsByYear W20481428932014 @default.
• W2048142893 countsByYear W20481428932015 @default.
• W2048142893 countsByYear W20481428932016 @default.
• W2048142893 countsByYear W20481428932017 @default.
• W2048142893 countsByYear W20481428932018 @default.
• W2048142893 countsByYear W20481428932019 @default.
• W2048142893 countsByYear W20481428932020 @default.
• W2048142893 countsByYear W20481428932021 @default.
• W2048142893 countsByYear W20481428932022 @default.
• W2048142893 countsByYear W20481428932023 @default.
• W2048142893 crossrefType "journal-article" @default.
• W2048142893 hasAuthorship W2048142893A5062422288 @default.
• W2048142893 hasAuthorship W2048142893A5071961044 @default.
• W2048142893 hasBestOaLocation W20481428931 @default.
• W2048142893 hasConcept C120665830 @default.
• W2048142893 hasConcept C121332964 @default.
• W2048142893 hasConcept C126322002 @default.
• W2048142893 hasConcept C142724271 @default.
• W2048142893 hasConcept C168563851 @default.
• W2048142893 hasConcept C17744445 @default.
• W2048142893 hasConcept C187212893 @default.
• W2048142893 hasConcept C189708586 @default.
• W2048142893 hasConcept C199539241 @default.
• W2048142893 hasConcept C204787440 @default.
• W2048142893 hasConcept C2779473830 @default.
• W2048142893 hasConcept C3020774429 @default.
• W2048142893 hasConcept C512399662 @default.
• W2048142893 hasConcept C535046627 @default.
• W2048142893 hasConcept C61511704 @default.
• W2048142893 hasConcept C71924100 @default.
• W2048142893 hasConcept C95190672 @default.
• W2048142893 hasConceptScore W2048142893C120665830 @default.
• W2048142893 hasConceptScore W2048142893C121332964 @default.
• W2048142893 hasConceptScore W2048142893C126322002 @default.
• W2048142893 hasConceptScore W2048142893C142724271 @default.
• W2048142893 hasConceptScore W2048142893C168563851 @default.
• W2048142893 hasConceptScore W2048142893C17744445 @default.
• W2048142893 hasConceptScore W2048142893C187212893 @default.
• W2048142893 hasConceptScore W2048142893C189708586 @default.
• W2048142893 hasConceptScore W2048142893C199539241 @default.

• next