Matches in SemOpenAlex for { <https://semopenalex.org/work/W2048149767> ?p ?o ?g. }
- W2048149767 endingPage "229" @default.
- W2048149767 startingPage "219" @default.
- W2048149767 abstract "The current study examined the long-term effects of infraorbital nerve (ION) axoplasmic transport attenuation with vinblastine on the organization of trigeminal (V) primary afferents and central vibrissae-related patterns. Retrograde tracing and single unit recording were used to evaluate the innervation of vibrissae follicles in adult (P > 60) rats that sustained application of vinblastine to the ION at birth. Single units recorded from vinblastine-treated animals yielded responses to deflection of a single vibrissa, and a significantly (P < 0.001) higher percentage of these cells (85.7%) showed rapidly adapting responses compared with normal rats (42.2%). Retrograde tracing revealed a qualitatively and normal distribution of V ganglion cells innervating A-row and E-row vibrissae follicles in vinblastine-treated rats. Transganglionic tracing with horseradish peroxidase (HRP) demonstrated a qualitatively and quantitatively normal somatotopic organization of vibrissae follicle input to V nucleus principalis (PrV) and V subnucleus interpolaris (SpI) in the vinblastine-treated animals. Despite the nearly normal mapping of V ganglion cell axons onto the vibrissae follicles and brainstem, staining for either cytochrome oxidase (CO) or parvalbumin failed to reveal vibrissae-related patterns in PrV, SpI, or the magnocellular portion of V subnucleus caudalis in these animals. Labelling of thalamocortical afferents with HRP and staining for CO also failed to reveal a cortical vibrissae-related pattern in the vinblastine-treated rats. The present results indicate that although transient attenuation of axoplasmic transport with vinblastine has limited effects on the peripheral and central projections of surviving V primary afferents, it permanently disrupts the normal development and maintenance of central vibrissae-related patterns." @default.
- W2048149767 created "2016-06-24" @default.
- W2048149767 creator A5000584616 @default.
- W2048149767 creator A5058897879 @default.
- W2048149767 creator A5062497049 @default.
- W2048149767 creator A5073929829 @default.
- W2048149767 creator A5084645345 @default.
- W2048149767 date "1997-05-05" @default.
- W2048149767 modified "2023-10-16" @default.
- W2048149767 title "Long-term effects of neonatal axoplasmic transport attenuation on the organization of the rat's trigeminal system" @default.
- W2048149767 cites W1623154787 @default.
- W2048149767 cites W1893922108 @default.
- W2048149767 cites W1899716694 @default.
- W2048149767 cites W1969538982 @default.
- W2048149767 cites W1972059468 @default.
- W2048149767 cites W1973524503 @default.
- W2048149767 cites W1981073375 @default.
- W2048149767 cites W1988585965 @default.
- W2048149767 cites W1989670552 @default.
- W2048149767 cites W1998065875 @default.
- W2048149767 cites W2006837670 @default.
- W2048149767 cites W2012540168 @default.
- W2048149767 cites W2013600505 @default.
- W2048149767 cites W2021358642 @default.
- W2048149767 cites W2027707958 @default.
- W2048149767 cites W2028004089 @default.
- W2048149767 cites W2031159964 @default.
- W2048149767 cites W2032455382 @default.
- W2048149767 cites W2035753658 @default.
- W2048149767 cites W2039289087 @default.
- W2048149767 cites W2042437835 @default.
- W2048149767 cites W2048181679 @default.
- W2048149767 cites W2048673469 @default.
- W2048149767 cites W2049666592 @default.
- W2048149767 cites W2050913048 @default.
- W2048149767 cites W2052973145 @default.
- W2048149767 cites W2068381596 @default.
- W2048149767 cites W2070811346 @default.
- W2048149767 cites W2072029388 @default.
- W2048149767 cites W2076765847 @default.
- W2048149767 cites W2077960291 @default.
- W2048149767 cites W2080743678 @default.
- W2048149767 cites W2094295017 @default.
- W2048149767 cites W2106298745 @default.
- W2048149767 cites W2108841190 @default.
- W2048149767 cites W2110467443 @default.
- W2048149767 cites W2140473620 @default.
- W2048149767 cites W2751481223 @default.
- W2048149767 cites W4243560547 @default.
- W2048149767 doi "https://doi.org/10.1002/(sici)1096-9861(19970505)381:2<219::aid-cne8>3.0.co;2-6" @default.
- W2048149767 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9130670" @default.
- W2048149767 hasPublicationYear "1997" @default.
- W2048149767 type Work @default.
- W2048149767 sameAs 2048149767 @default.
- W2048149767 citedByCount "8" @default.
- W2048149767 countsByYear W20481497672012 @default.
- W2048149767 countsByYear W20481497672015 @default.
- W2048149767 crossrefType "journal-article" @default.
- W2048149767 hasAuthorship W2048149767A5000584616 @default.
- W2048149767 hasAuthorship W2048149767A5058897879 @default.
- W2048149767 hasAuthorship W2048149767A5062497049 @default.
- W2048149767 hasAuthorship W2048149767A5073929829 @default.
- W2048149767 hasAuthorship W2048149767A5084645345 @default.
- W2048149767 hasConcept C105702510 @default.
- W2048149767 hasConcept C141547260 @default.
- W2048149767 hasConcept C169760540 @default.
- W2048149767 hasConcept C181199279 @default.
- W2048149767 hasConcept C185592680 @default.
- W2048149767 hasConcept C2776352249 @default.
- W2048149767 hasConcept C2776378061 @default.
- W2048149767 hasConcept C2777676563 @default.
- W2048149767 hasConcept C2780767800 @default.
- W2048149767 hasConcept C2781334511 @default.
- W2048149767 hasConcept C529278444 @default.
- W2048149767 hasConcept C55493867 @default.
- W2048149767 hasConcept C70192387 @default.
- W2048149767 hasConcept C86803240 @default.
- W2048149767 hasConcept C94487597 @default.
- W2048149767 hasConceptScore W2048149767C105702510 @default.
- W2048149767 hasConceptScore W2048149767C141547260 @default.
- W2048149767 hasConceptScore W2048149767C169760540 @default.
- W2048149767 hasConceptScore W2048149767C181199279 @default.
- W2048149767 hasConceptScore W2048149767C185592680 @default.
- W2048149767 hasConceptScore W2048149767C2776352249 @default.
- W2048149767 hasConceptScore W2048149767C2776378061 @default.
- W2048149767 hasConceptScore W2048149767C2777676563 @default.
- W2048149767 hasConceptScore W2048149767C2780767800 @default.
- W2048149767 hasConceptScore W2048149767C2781334511 @default.
- W2048149767 hasConceptScore W2048149767C529278444 @default.
- W2048149767 hasConceptScore W2048149767C55493867 @default.
- W2048149767 hasConceptScore W2048149767C70192387 @default.
- W2048149767 hasConceptScore W2048149767C86803240 @default.
- W2048149767 hasConceptScore W2048149767C94487597 @default.
- W2048149767 hasIssue "2" @default.
- W2048149767 hasLocation W20481497671 @default.
- W2048149767 hasLocation W20481497672 @default.
- W2048149767 hasOpenAccess W2048149767 @default.
- W2048149767 hasPrimaryLocation W20481497671 @default.