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• W2048231748 abstract "In human genetic identification the selection of highly polymorphic markers it is very important in order to obtain a high discrimination power even when the number of loci is limited. STR typing continues to be the most robust and reliable method for samples with small amounts of purified and non-degraded DNA. Nonetheless, STR typing has some limitations, such as large amplicon sizes between 150 and 450 base pairs, which can contribute for poor results in challenging forensic samples [ [1] Manta F. Caiafa A. Pereira R. Silva D. Amorim A. Carvalho E.F. Gusmão L. InDel markers: genetic diversity of 38 polymorphisms in Brazilian populations and application in a paternity investigation with post mortem material. Forensic Sci. Int. Genet. 2012; 6: 658-661 Abstract Full Text Full Text PDF PubMed Scopus (30) Google Scholar ], and also some technical issues like the presence of artefacts, like stutter products and pull ups which can introduce some ambiguity to analysis, specially, in mixture DNA samples [ [2] LaRue B.L. Ge J. King J.L. Budowle B. A validation study of the Qiagen Investigator DIPplex® kit; an INDEL-based assay for human identification. Int. J. Legal Med. 2012; 126: 533-540https://doi.org/10.1007/s00414-012-0667-9 Crossref PubMed Scopus (82) Google Scholar ]." @default.
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• W2048231748 date "2013-07-01" @default.
• W2048231748 modified "2023-10-14" @default.
• W2048231748 title "Genetic portrait of south Portugal population with InDel markers" @default.
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• W2048231748 doi "https://doi.org/10.1016/j.fsigen.2013.03.009" @default.
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