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- W2048250854 abstract "Abstract The purpose of this study was to evaluate what effects distension of the stomach would have on the discharge rate of cerebral cortical epileptogemic foci in cats. Epileptiform spiking was produced by focal freezing or topical application of penicillin. Intragastric pressure was increased by the inflation of an intraluminal latex balloon. Results showed that increases in intragastric pressure produced a decrease in epileptiform spike discharge rate in some preparations. Decreases in or the sudden release of intragastric pressure often produced an enhancement or “rebound” of epileptiform spiking. These findings agree with earlier reports from our laboratory in which passive distension of the urinary bladder or increased intracranial pressure produced similar results. We suggest that the decrease in spike rate may be due to the desynchronizing effect of afferent input produced by stomach distension. In this regard, sensory activity initiated by the gastric stretch receptors probably play a major role." @default.
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- W2048250854 date "1981-08-01" @default.
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- W2048250854 title "Changes in the rate of cortical epileptiform activity by increased intragastric pressure in cats" @default.
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- W2048250854 doi "https://doi.org/10.1016/0014-4886(81)90287-9" @default.
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