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- W2048257064 abstract "The surface activity of tracheal-bronchial secretions of 37 patients with and without chronic pulmonary disease were measured before and during inhalation anaesthesia. Patients with pulmonary disease (PD) had significantly higher mean minimal surface tensions of secretions (γ mins) before anaesthesia than those without disease (PN). Halothane, a fat soluble anaesthetic, significantly elevated secretion γ mins in PN patients but did not affect those with PD. Nitrous oxide, a gas not soluble in fat, did not change secretion γ mins in PN patients but significantly decreased these values in those with PD. These findings suggest that positive pressure ventilation can increase surfactant activity in patients with pulmonary disease but concomitant use of a fat soluble inhalation anaesthetic may overcome the benefits of such therapy." @default.
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- W2048257064 date "1973-05-01" @default.
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- W2048257064 title "The effects of general anaesthesia on the surface tension of secretions in the upper airway in patients with and without pulmonary disease" @default.
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