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• W2048287217 abstract "Purpose To determine diagnostic features of tuberculous peritonitis (TBP) in the absence and presence of chronic liver disease. Patients and methods Thirty-four patients with TBP (13 without [Group I] and 21 with chronic liver disease [Group II]) and 26 controls with cirrhosis and uninfected ascites (Group III) were studied. Results The clinical features in Groups I and II were similar and all patients had elevated ascitic fluid total mononuclear cell count. In Groups I, II, and III, respectively, ascitic fluid protein was >25 g/L in 100% (13/13), 70% (14/20), and 0% (0/26); serum-ascites albumin gradient (SAAG) was >11 g/L in 0% (0/13), 52% (11/21), and 96% (25/26) (0% [0/13], 71% [15/21], and 96% [25/26] after correction for serum globulin); and ascitic fluid lactate dehydrogenase (LDH) level was >90 U/L in 100% (12/12), 84% (16/19), and 0% (0/20), respectively. In Groups I and II combined, ascitic fluid acid-fast stain was negative in all but Mycobacterium tuberculosis culture was positive in 45% (10/22); peritoneal nodules occurred in 94% (31/33), granulomas in 93% (28/30), and positive peritoneal M tuberculosis culture in 63% (10/16). Conclusions In patients with suspected TBP, ascitic fluid protein of >25 g/L. SAAG of <11 g/L and LDH of >90 U/L have high sensitivity for the disease. With coexistent chronic liver disease, a lower protein level and higher SAAG are usually not helpful but LDH >90 U/L is a useful parameter for screening. Diagnosis is best confirmed by laparoscopy with peritoneal biopsy and M tuberculosis culture. To determine diagnostic features of tuberculous peritonitis (TBP) in the absence and presence of chronic liver disease. Thirty-four patients with TBP (13 without [Group I] and 21 with chronic liver disease [Group II]) and 26 controls with cirrhosis and uninfected ascites (Group III) were studied. The clinical features in Groups I and II were similar and all patients had elevated ascitic fluid total mononuclear cell count. In Groups I, II, and III, respectively, ascitic fluid protein was >25 g/L in 100% (13/13), 70% (14/20), and 0% (0/26); serum-ascites albumin gradient (SAAG) was >11 g/L in 0% (0/13), 52% (11/21), and 96% (25/26) (0% [0/13], 71% [15/21], and 96% [25/26] after correction for serum globulin); and ascitic fluid lactate dehydrogenase (LDH) level was >90 U/L in 100% (12/12), 84% (16/19), and 0% (0/20), respectively. In Groups I and II combined, ascitic fluid acid-fast stain was negative in all but Mycobacterium tuberculosis culture was positive in 45% (10/22); peritoneal nodules occurred in 94% (31/33), granulomas in 93% (28/30), and positive peritoneal M tuberculosis culture in 63% (10/16). In patients with suspected TBP, ascitic fluid protein of >25 g/L. SAAG of <11 g/L and LDH of >90 U/L have high sensitivity for the disease. With coexistent chronic liver disease, a lower protein level and higher SAAG are usually not helpful but LDH >90 U/L is a useful parameter for screening. Diagnosis is best confirmed by laparoscopy with peritoneal biopsy and M tuberculosis culture." @default.
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• W2048287217 title "Diagnostic features of tuberculous peritonitis in the absence and presence of chronic liver disease: A case control study" @default.
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• W2048287217 doi "https://doi.org/10.1016/s0002-9343(97)89456-9" @default.
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