Matches in SemOpenAlex for { <https://semopenalex.org/work/W2048339719> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2048339719 endingPage "357" @default.
- W2048339719 startingPage "354" @default.
- W2048339719 abstract "AmpC β-lactamases are enzymes that hydrolyze all β-lactam antibiotics except cefipime and imipenem. Currently, there is no standard phenotypic method for detection of such enzymes. This study aims to report the use of sodium salicylate for AmpC β-lactamases detection and to compare its sensitivity and specificity to other commonly known inhibitors. A total of 135 clinical isolates were used to test the effectiveness of sodium salicylate in detection of plasmid- as well as chromosomally encoded AmpC β-lactamases. All isolates were tested by multiplex PCR testing as well as inhibitor-based methods using cloxacillin, phenylboronic acid and sodium salicylate for the detection of AmpC enzymes. Four isolates were confirmed as producers of plasmid-encoded AmpC β-lactamase and a single isolate was confirmed to have both plasmid and chromosomal genes. Cloxacillin and phenylyboronic acid failed to detect most of the plasmid-encoded enzymes. Sodium salicylate was able to detect the Escherichia coli isolates with plasmid-encoded enzymes in addition to few other isolates that were chromosomally mediated. The sensitivity and specificity of sodium salicylate was 50% and 93%, respectively, higher than those of other known inhibitors. We thus conclude that sodium salicylate can be reliably used as an inhibitor in the detection of plasmid-encoded AmpC enzymes in E. coli." @default.
- W2048339719 created "2016-06-24" @default.
- W2048339719 creator A5003927660 @default.
- W2048339719 creator A5062038042 @default.
- W2048339719 creator A5087057508 @default.
- W2048339719 date "2012-12-01" @default.
- W2048339719 modified "2023-10-14" @default.
- W2048339719 title "Detection of AmpC beta-lactamases using sodium salicylate" @default.
- W2048339719 cites W2034314930 @default.
- W2048339719 cites W2039913627 @default.
- W2048339719 cites W2055043387 @default.
- W2048339719 cites W2059689725 @default.
- W2048339719 cites W2088942075 @default.
- W2048339719 cites W2098342846 @default.
- W2048339719 cites W2099001508 @default.
- W2048339719 cites W2099303284 @default.
- W2048339719 cites W2100311333 @default.
- W2048339719 cites W2111190718 @default.
- W2048339719 cites W2113433563 @default.
- W2048339719 cites W2114062705 @default.
- W2048339719 cites W2121867408 @default.
- W2048339719 cites W2126873899 @default.
- W2048339719 cites W2129825395 @default.
- W2048339719 cites W2131640369 @default.
- W2048339719 cites W2134352676 @default.
- W2048339719 cites W2138205191 @default.
- W2048339719 cites W2148492106 @default.
- W2048339719 cites W2154644043 @default.
- W2048339719 cites W2160228456 @default.
- W2048339719 cites W2163870515 @default.
- W2048339719 cites W2163999241 @default.
- W2048339719 cites W2171929210 @default.
- W2048339719 doi "https://doi.org/10.1016/j.mimet.2012.09.035" @default.
- W2048339719 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23059062" @default.
- W2048339719 hasPublicationYear "2012" @default.
- W2048339719 type Work @default.
- W2048339719 sameAs 2048339719 @default.
- W2048339719 citedByCount "3" @default.
- W2048339719 countsByYear W20483397192017 @default.
- W2048339719 countsByYear W20483397192020 @default.
- W2048339719 crossrefType "journal-article" @default.
- W2048339719 hasAuthorship W2048339719A5003927660 @default.
- W2048339719 hasAuthorship W2048339719A5062038042 @default.
- W2048339719 hasAuthorship W2048339719A5087057508 @default.
- W2048339719 hasConcept C104317684 @default.
- W2048339719 hasConcept C181199279 @default.
- W2048339719 hasConcept C185592680 @default.
- W2048339719 hasConcept C22744801 @default.
- W2048339719 hasConcept C2776021129 @default.
- W2048339719 hasConcept C2779134981 @default.
- W2048339719 hasConcept C2779631663 @default.
- W2048339719 hasConcept C2780408477 @default.
- W2048339719 hasConcept C501593827 @default.
- W2048339719 hasConcept C547475151 @default.
- W2048339719 hasConcept C55493867 @default.
- W2048339719 hasConcept C86803240 @default.
- W2048339719 hasConcept C89423630 @default.
- W2048339719 hasConcept C94665300 @default.
- W2048339719 hasConcept C98274493 @default.
- W2048339719 hasConceptScore W2048339719C104317684 @default.
- W2048339719 hasConceptScore W2048339719C181199279 @default.
- W2048339719 hasConceptScore W2048339719C185592680 @default.
- W2048339719 hasConceptScore W2048339719C22744801 @default.
- W2048339719 hasConceptScore W2048339719C2776021129 @default.
- W2048339719 hasConceptScore W2048339719C2779134981 @default.
- W2048339719 hasConceptScore W2048339719C2779631663 @default.
- W2048339719 hasConceptScore W2048339719C2780408477 @default.
- W2048339719 hasConceptScore W2048339719C501593827 @default.
- W2048339719 hasConceptScore W2048339719C547475151 @default.
- W2048339719 hasConceptScore W2048339719C55493867 @default.
- W2048339719 hasConceptScore W2048339719C86803240 @default.
- W2048339719 hasConceptScore W2048339719C89423630 @default.
- W2048339719 hasConceptScore W2048339719C94665300 @default.
- W2048339719 hasConceptScore W2048339719C98274493 @default.
- W2048339719 hasIssue "3" @default.
- W2048339719 hasLocation W20483397191 @default.
- W2048339719 hasLocation W20483397192 @default.
- W2048339719 hasOpenAccess W2048339719 @default.
- W2048339719 hasPrimaryLocation W20483397191 @default.
- W2048339719 hasRelatedWork W1985426194 @default.
- W2048339719 hasRelatedWork W2013738070 @default.
- W2048339719 hasRelatedWork W2041543427 @default.
- W2048339719 hasRelatedWork W2048339719 @default.
- W2048339719 hasRelatedWork W2135369330 @default.
- W2048339719 hasRelatedWork W2318106903 @default.
- W2048339719 hasRelatedWork W2613338243 @default.
- W2048339719 hasRelatedWork W3165233450 @default.
- W2048339719 hasRelatedWork W58688778 @default.
- W2048339719 hasRelatedWork W96819689 @default.
- W2048339719 hasVolume "91" @default.
- W2048339719 isParatext "false" @default.
- W2048339719 isRetracted "false" @default.
- W2048339719 magId "2048339719" @default.
- W2048339719 workType "article" @default.