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- W2048377194 abstract "The administration to chicks of hormones which decidedly affected blood glucose, liver glycogen, and muscle glycogen was shown to have no effect, except in two cases, upon the glycogen content of the glycogen body. Corticosterone in one experiment and epinephrine in one experiment out of five increased glycogen-body glycogen. The hormones used included regular insulin, glucagon-free insulin, glucagon, epinephrine, cortisone, hydrocortisone, corticosterone, and mammalian growth hormone. Chicks fasting for as long as 5 days after hatching failed to show significant changes in glycogen-body glycogen concentration. Glycogen body weight and total glycogen increased gradually with age during an 11-week period. Glycogen concentration reached a peak (32%) at 3 weeks, gradually declined to the hatching level (25%) at about one month, then continued to fall and reached 21% by the eleventh week. Week-old chicks were killed 3, 8, 18, or 48 hours after injection with 50 μc of glucose C14, and the level of isotope in the glucogen-body glycogen was determined. The glycogen was digested with β-amylase to separately determine the activities of the peripheral tiers (maltose) and inner core (limit dextrin) of the glycogen. The specific activity of glycogen-body glycogen as per cent of the injected specific activity was insignificant at 3 hours and 0.015%, 0.040% and 0.016% at 8, 18, and 48 hours respectively, indicating an incorporation and release of the glucose C14 during the 48 hour period. The replacement of glucosyl units was greater in the maltose fraction of the glycogen than in the limit dextrin. These changes are interpreted as an indication that although the glycogen concentration remained constant, glycogenesis and glycogenolysis occurred." @default.
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- W2048377194 date "1963-04-01" @default.
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- W2048377194 title "Studies on the chick glycogen body: Effects of hormones and normal glycogen turnover" @default.
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- W2048377194 doi "https://doi.org/10.1016/0016-6480(63)90037-6" @default.
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