FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2048381855> ?p ?o ?g. }

• W2048381855 endingPage "392" @default.
• W2048381855 startingPage "386" @default.
• W2048381855 abstract "The purpose of this work was to evaluate protective activity against brain cyst formation in BALB/c mice intranasally vaccinated with recombinant proteins from Toxoplasma gondii. The recombinant proteins rROP2, rGRA5 and rGRA7 were used in vaccine preparation. Thirty-three female mice were divided into three groups, these animals received two doses by intranasal route at days 0 and 21 as follows; group 1 (G1, n = 11) received 12.5 μg of each recombinant protein plus 0.5 μg of cholera toxin, group 2 (G2, n = 11) received phosphate buffer saline (PBS) plus 0.5 μg of cholera toxin, and group 3 (G3, n = 11) received PBS only. At challenge day (day 33) three animals from each group were euthanatized for IgA measure from intestine. Mice were infected orally with 50 cysts from the VEG strain at day 33. At challenge day the G1 animals had high immunoglobulin A levels, however, they only showed IgG antibody titers against rROP2 and rGRA7. Animals from G1 also exhibited strong resistance to cyst formation compared with the control group (G3, P < 0.05). However, we did not observe differences in protection against brain cyst formation between G1 and G2 (P > 0.1). These results indicate that intranasal immunization in BALB/c mice with recombinant proteins rROP2, rGRA5 and rGRA7 associated with cholera toxin induced partial protection, when compared with G3, against tissue cyst formation after oral infection with tissue cysts from T. gondii." @default.
• W2048381855 created "2016-06-24" @default.
• W2048381855 creator A5008905709 @default.
• W2048381855 creator A5009966096 @default.
• W2048381855 creator A5019080581 @default.
• W2048381855 creator A5020948273 @default.
• W2048381855 creator A5026962585 @default.
• W2048381855 creator A5042306016 @default.
• W2048381855 creator A5072461118 @default.
• W2048381855 creator A5083991905 @default.
• W2048381855 date "2008-03-01" @default.
• W2048381855 modified "2023-10-01" @default.
• W2048381855 title "Toxoplasma gondii: Evaluation of an intranasal vaccine using recombinant proteins against brain cyst formation in BALB/c mice" @default.
• W2048381855 cites W1591678521 @default.
• W2048381855 cites W1935780090 @default.
• W2048381855 cites W1958713593 @default.
• W2048381855 cites W1965922439 @default.
• W2048381855 cites W1973681405 @default.
• W2048381855 cites W1980467313 @default.
• W2048381855 cites W1981053719 @default.
• W2048381855 cites W1986091067 @default.
• W2048381855 cites W1987880248 @default.
• W2048381855 cites W1996130689 @default.
• W2048381855 cites W1997613969 @default.
• W2048381855 cites W2006363933 @default.
• W2048381855 cites W2014507720 @default.
• W2048381855 cites W2024965710 @default.
• W2048381855 cites W2038251648 @default.
• W2048381855 cites W2039221528 @default.
• W2048381855 cites W2063169921 @default.
• W2048381855 cites W2063844573 @default.
• W2048381855 cites W2069242533 @default.
• W2048381855 cites W2069487431 @default.
• W2048381855 cites W2080763801 @default.
• W2048381855 cites W2091061276 @default.
• W2048381855 cites W2100837269 @default.
• W2048381855 cites W2101108802 @default.
• W2048381855 cites W2112554102 @default.
• W2048381855 cites W2115188616 @default.
• W2048381855 cites W2120482236 @default.
• W2048381855 cites W2138614218 @default.
• W2048381855 cites W2141587888 @default.
• W2048381855 cites W2153249510 @default.
• W2048381855 cites W2157862649 @default.
• W2048381855 cites W2168752254 @default.
• W2048381855 cites W2316745234 @default.
• W2048381855 cites W4293231114 @default.
• W2048381855 doi "https://doi.org/10.1016/j.exppara.2007.10.002" @default.
• W2048381855 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18154953" @default.
• W2048381855 hasPublicationYear "2008" @default.
• W2048381855 type Work @default.
• W2048381855 sameAs 2048381855 @default.
• W2048381855 citedByCount "41" @default.
• W2048381855 countsByYear W20483818552012 @default.
• W2048381855 countsByYear W20483818552013 @default.
• W2048381855 countsByYear W20483818552014 @default.
• W2048381855 countsByYear W20483818552015 @default.
• W2048381855 countsByYear W20483818552016 @default.
• W2048381855 countsByYear W20483818552017 @default.
• W2048381855 countsByYear W20483818552018 @default.
• W2048381855 countsByYear W20483818552019 @default.
• W2048381855 countsByYear W20483818552020 @default.
• W2048381855 crossrefType "journal-article" @default.
• W2048381855 hasAuthorship W2048381855A5008905709 @default.
• W2048381855 hasAuthorship W2048381855A5009966096 @default.
• W2048381855 hasAuthorship W2048381855A5019080581 @default.
• W2048381855 hasAuthorship W2048381855A5020948273 @default.
• W2048381855 hasAuthorship W2048381855A5026962585 @default.
• W2048381855 hasAuthorship W2048381855A5042306016 @default.
• W2048381855 hasAuthorship W2048381855A5072461118 @default.
• W2048381855 hasAuthorship W2048381855A5083991905 @default.
• W2048381855 hasConcept C104317684 @default.
• W2048381855 hasConcept C142724271 @default.
• W2048381855 hasConcept C159047783 @default.
• W2048381855 hasConcept C159654299 @default.
• W2048381855 hasConcept C203014093 @default.
• W2048381855 hasConcept C22889606 @default.
• W2048381855 hasConcept C2777006276 @default.
• W2048381855 hasConcept C2777367657 @default.
• W2048381855 hasConcept C2778062946 @default.
• W2048381855 hasConcept C2778128430 @default.
• W2048381855 hasConcept C2780597408 @default.
• W2048381855 hasConcept C2780801004 @default.
• W2048381855 hasConcept C32611913 @default.
• W2048381855 hasConcept C40767141 @default.
• W2048381855 hasConcept C55493867 @default.
• W2048381855 hasConcept C71924100 @default.
• W2048381855 hasConcept C85663871 @default.
• W2048381855 hasConcept C86803240 @default.
• W2048381855 hasConcept C89423630 @default.
• W2048381855 hasConceptScore W2048381855C104317684 @default.
• W2048381855 hasConceptScore W2048381855C142724271 @default.
• W2048381855 hasConceptScore W2048381855C159047783 @default.
• W2048381855 hasConceptScore W2048381855C159654299 @default.
• W2048381855 hasConceptScore W2048381855C203014093 @default.
• W2048381855 hasConceptScore W2048381855C22889606 @default.
• W2048381855 hasConceptScore W2048381855C2777006276 @default.
• W2048381855 hasConceptScore W2048381855C2777367657 @default.

• next