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- W2048386181 abstract "A report is presented of a follicular dendritlc cell (FDC) tumor arising In the lymph nodes and Inguen of a 55-year-old Japanese female, who had suffered from schizophrenla for 25 years. The left submandibular lymph nodes had completely lost their normal architecture, except for the capsule, due to tumor cell infiltration. Occaslonal nodular structures resembling epltheliold granulomas, attributable, at least In part, to follicular Involvement of tumor cells, were observed. These nodules were composed of epithellold- or fibroblast-like tumor cells forming interwoven fascicles, to which small lymphocytes were attached. Tumor cells were also scattered in the internodular areas. For more atyplcal tumor cells, arranged in a sheet-like structure, were present In the inguinal specimen, the tumor cells of which expressed Ki-M4p, CD21, CD35 and other antigens known to be expressed on FDC. Furthermore, they also expressed the monocytdmacrophage antlgens, α1-antltrypsin, α-antlchymotrypsin, lysozyme, CD14, CD33, CD68 and Mac387 and fibroblastic antigen. Ultrastructural studies demonstrated lysosomal granules as well as a few desmosomes, Indicating the tumor cells possessed fibrohistiocytic and FDC characteristics." @default.
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- W2048386181 date "1997-10-01" @default.
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- W2048386181 title "Follicular dendritic cell tumor with histiocytic characteristics and fibroblastic antigen" @default.
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- W2048386181 doi "https://doi.org/10.1111/j.1440-1827.1997.tb04446.x" @default.
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