FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2048408953> ?p ?o ?g. }

• W2048408953 endingPage "6115" @default.
• W2048408953 startingPage "6108" @default.
• W2048408953 abstract "The Na(V)1.7 ion channel is an attractive target for development of potential analgesic drugs based on strong genetic links between mutations in the gene coding for the channel protein and inheritable pain conditions. The (S)-N-chroman-3-ylcarboxamide series, exemplified by 1, was used as a starting point for development of new channel blockers, resulting in the phenethyl nicotinamide series. The structure and activity relationship for this series was established and the metabolic issues of early analogues were addressed by appropriate substitutions. Compound 33 displayed acceptable overall in vitro properties and in vivo rat PK profile." @default.
• W2048408953 created "2016-06-24" @default.
• W2048408953 creator A5006203194 @default.
• W2048408953 creator A5006394484 @default.
• W2048408953 creator A5021039603 @default.
• W2048408953 creator A5021410617 @default.
• W2048408953 creator A5024053767 @default.
• W2048408953 creator A5024964171 @default.
• W2048408953 creator A5044410277 @default.
• W2048408953 creator A5045086249 @default.
• W2048408953 creator A5056662603 @default.
• W2048408953 creator A5057201256 @default.
• W2048408953 creator A5058745699 @default.
• W2048408953 creator A5058787627 @default.
• W2048408953 creator A5062978215 @default.
• W2048408953 creator A5084005166 @default.
• W2048408953 creator A5038506508 @default.
• W2048408953 date "2012-10-01" @default.
• W2048408953 modified "2023-10-16" @default.
• W2048408953 title "Phenethyl nicotinamides, a novel class of NaV1.7 channel blockers: Structure and activity relationship" @default.
• W2048408953 cites W1976268173 @default.
• W2048408953 cites W2018631823 @default.
• W2048408953 cites W2021995068 @default.
• W2048408953 cites W2029226207 @default.
• W2048408953 cites W2038714089 @default.
• W2048408953 cites W2098007639 @default.
• W2048408953 cites W2101016189 @default.
• W2048408953 cites W2105403855 @default.
• W2048408953 cites W2108114952 @default.
• W2048408953 cites W2117162399 @default.
• W2048408953 cites W2118437002 @default.
• W2048408953 cites W2130972481 @default.
• W2048408953 cites W2138809708 @default.
• W2048408953 cites W4253853981 @default.
• W2048408953 doi "https://doi.org/10.1016/j.bmcl.2012.08.031" @default.
• W2048408953 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22939696" @default.
• W2048408953 hasPublicationYear "2012" @default.
• W2048408953 type Work @default.
• W2048408953 sameAs 2048408953 @default.
• W2048408953 citedByCount "7" @default.
• W2048408953 countsByYear W20484089532013 @default.
• W2048408953 countsByYear W20484089532014 @default.
• W2048408953 countsByYear W20484089532015 @default.
• W2048408953 countsByYear W20484089532017 @default.
• W2048408953 countsByYear W20484089532022 @default.
• W2048408953 crossrefType "journal-article" @default.
• W2048408953 hasAuthorship W2048408953A5006203194 @default.
• W2048408953 hasAuthorship W2048408953A5006394484 @default.
• W2048408953 hasAuthorship W2048408953A5021039603 @default.
• W2048408953 hasAuthorship W2048408953A5021410617 @default.
• W2048408953 hasAuthorship W2048408953A5024053767 @default.
• W2048408953 hasAuthorship W2048408953A5024964171 @default.
• W2048408953 hasAuthorship W2048408953A5038506508 @default.
• W2048408953 hasAuthorship W2048408953A5044410277 @default.
• W2048408953 hasAuthorship W2048408953A5045086249 @default.
• W2048408953 hasAuthorship W2048408953A5056662603 @default.
• W2048408953 hasAuthorship W2048408953A5057201256 @default.
• W2048408953 hasAuthorship W2048408953A5058745699 @default.
• W2048408953 hasAuthorship W2048408953A5058787627 @default.
• W2048408953 hasAuthorship W2048408953A5062978215 @default.
• W2048408953 hasAuthorship W2048408953A5084005166 @default.
• W2048408953 hasConcept C170493617 @default.
• W2048408953 hasConcept C178790620 @default.
• W2048408953 hasConcept C181199279 @default.
• W2048408953 hasConcept C185592680 @default.
• W2048408953 hasConcept C193042331 @default.
• W2048408953 hasConcept C202751555 @default.
• W2048408953 hasConcept C207001950 @default.
• W2048408953 hasConcept C2776250582 @default.
• W2048408953 hasConcept C2779728014 @default.
• W2048408953 hasConcept C2780820201 @default.
• W2048408953 hasConcept C50254741 @default.
• W2048408953 hasConcept C50952357 @default.
• W2048408953 hasConcept C537181965 @default.
• W2048408953 hasConcept C54355233 @default.
• W2048408953 hasConcept C55493867 @default.
• W2048408953 hasConcept C71240020 @default.
• W2048408953 hasConcept C71924100 @default.
• W2048408953 hasConcept C86803240 @default.
• W2048408953 hasConcept C98274493 @default.
• W2048408953 hasConceptScore W2048408953C170493617 @default.
• W2048408953 hasConceptScore W2048408953C178790620 @default.
• W2048408953 hasConceptScore W2048408953C181199279 @default.
• W2048408953 hasConceptScore W2048408953C185592680 @default.
• W2048408953 hasConceptScore W2048408953C193042331 @default.
• W2048408953 hasConceptScore W2048408953C202751555 @default.
• W2048408953 hasConceptScore W2048408953C207001950 @default.
• W2048408953 hasConceptScore W2048408953C2776250582 @default.
• W2048408953 hasConceptScore W2048408953C2779728014 @default.
• W2048408953 hasConceptScore W2048408953C2780820201 @default.
• W2048408953 hasConceptScore W2048408953C50254741 @default.
• W2048408953 hasConceptScore W2048408953C50952357 @default.
• W2048408953 hasConceptScore W2048408953C537181965 @default.
• W2048408953 hasConceptScore W2048408953C54355233 @default.
• W2048408953 hasConceptScore W2048408953C55493867 @default.
• W2048408953 hasConceptScore W2048408953C71240020 @default.
• W2048408953 hasConceptScore W2048408953C71924100 @default.
• W2048408953 hasConceptScore W2048408953C86803240 @default.

• next