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• W2048424449 abstract "The kinetics of neutrophilic granulocytes in the blood of rats were investigated using in vivo3H-TdR labelling and autoradiography. The radioactive precursor was administered by single injection, repeated injections at 5 hr intervals and continuous infusion. The appearance of labelled granulocytes in the blood and in the sputum was recorded up to 120 hr after tracer application. In contrast to results after a single injection of 3H-TdR, complete labelling of the blood granulocyte pool was achieved when the DNA precursor was given by continuous infusion or four repeated injections at 5 hr intervals. In the latter experiments, an exponential replacement of unlabelled blood granulocytes by labelled granulocytes could be demonstrated, the mean intravascular half-life being 5·7 hr. This figure is in good agreement with values obtained by isotopic techniques in other mammalian species." @default.
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• W2048424449 date "1973-07-01" @default.
• W2048424449 modified "2023-10-18" @default.
• W2048424449 title "KINETICS OF NEUTROPHILIC GRANULOCYTES IN THE BLOOD OF RATS" @default.
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• W2048424449 doi "https://doi.org/10.1111/j.1365-2184.1973.tb01625.x" @default.
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