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- W2048484313 abstract "Intraspinal injection of levorphanol (3 micrograms) at the lumbar area of the leopard frog, Rana pipiens, induced analgesia which was completely blocked by co-injection of naloxone (3 micrograms), whereas dextrorphan (3 micrograms) induced analgesia which was unaffected by naloxone. Subcutaneous levorphanol (20 or 80 mg/kg) induced a dose-dependent analgesia which was blocked by concurrent naloxone (2 mg/kg), while only the higher dose of dextrorphan (80 mg/kg) induced analgesia which was unaffected by concurrent naloxone at 8 or 80 mg/kg. These data are the first to indicate naloxone-insensitive, dextrorphan-induced analgesia." @default.
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- W2048484313 date "1984-05-01" @default.
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- W2048484313 title "Naloxone blocks the analgesic action of levorphanol but not of dextrorphan in the leopard frog" @default.
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- W2048484313 doi "https://doi.org/10.1016/0006-8993(84)90418-9" @default.
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