Matches in SemOpenAlex for { <https://semopenalex.org/work/W2048493057> ?p ?o ?g. }
- W2048493057 abstract "In mammalian tissues, ultraweak chemiluminescence arising from biomolecule oxidation has been attributed to the radiative deactivation of singlet molecular oxygen [O2 (1Δg)] and electronically excited triplet carbonyl products involving dioxetane intermediates. Herein, we describe evidence of the generation of O2 (1Δg) in aqueous solution via energy transfer from excited triplet acetone. This involves thermolysis of 3,3,4,4-tetramethyl-1,2-dioxetane, a chemical source and horseradish peroxidase-catalyzed oxidation of 2-methylpropanal, as an enzymatic source. Both sources of excited carbonyls showed characteristic light emission at 1,270 nm, directly indicative of the monomolecular decay of O2 (1Δg). Indirect analysis of O2 (1Δg) by electron paramagnetic resonance using the chemical trap 2,2,6,6-tetramethylpiperidine showed the formation of 2,2,6,6-tetramethylpiperidine-1-oxyl. Using [18O]-labeled triplet, ground state molecular oxygen [18O2 (3Σg-)], chemical trapping of 18O2 (1Δg) with disodium salt of anthracene-9,10-diyldiethane-2,1-diyl disulfate yielding the corresponding double-[18O]-labeled 9,10-endoperoxide, was detected through mass spectrometry. This corroborates formation of O2 (1Δg). Altogether, photoemission and chemical trapping studies clearly demonstrate that chemically and enzymatically nascent excited carbonyl generates 18O2 (1Δg) by triplet-triplet energy transfer to ground state oxygen O2 (3Σg−) and supports the long formulated hypothesis of O2 (1Δg) involvement in physiological and pathophysiological events that might take place in tissues in the absence of light." @default.
- W2048493057 created "2016-06-24" @default.
- W2048493057 creator A5009571663 @default.
- W2048493057 creator A5026957413 @default.
- W2048493057 creator A5032830211 @default.
- W2048493057 creator A5039860353 @default.
- W2048493057 creator A5045607529 @default.
- W2048493057 creator A5063314670 @default.
- W2048493057 creator A5076546003 @default.
- W2048493057 creator A5078844747 @default.
- W2048493057 creator A5080887968 @default.
- W2048493057 creator A5090375510 @default.
- W2048493057 creator A5091525666 @default.
- W2048493057 date "2014-08-04" @default.
- W2048493057 modified "2023-10-16" @default.
- W2048493057 title "Excited singlet molecular O2 (1Δg) is generated enzymatically from excited carbonyls in the dark" @default.
- W2048493057 cites W1490575297 @default.
- W2048493057 cites W1517330770 @default.
- W2048493057 cites W1572331504 @default.
- W2048493057 cites W1597626465 @default.
- W2048493057 cites W1616654149 @default.
- W2048493057 cites W1965357424 @default.
- W2048493057 cites W1970359533 @default.
- W2048493057 cites W1972443569 @default.
- W2048493057 cites W1981167937 @default.
- W2048493057 cites W1983024911 @default.
- W2048493057 cites W1984209014 @default.
- W2048493057 cites W1984452969 @default.
- W2048493057 cites W1984644249 @default.
- W2048493057 cites W1985039619 @default.
- W2048493057 cites W1988765421 @default.
- W2048493057 cites W1989261646 @default.
- W2048493057 cites W1995684615 @default.
- W2048493057 cites W1996586422 @default.
- W2048493057 cites W1998675457 @default.
- W2048493057 cites W2002282826 @default.
- W2048493057 cites W2011205366 @default.
- W2048493057 cites W2011222045 @default.
- W2048493057 cites W2012005841 @default.
- W2048493057 cites W2016018176 @default.
- W2048493057 cites W2017299446 @default.
- W2048493057 cites W2021489803 @default.
- W2048493057 cites W2027307384 @default.
- W2048493057 cites W2029571838 @default.
- W2048493057 cites W2030641103 @default.
- W2048493057 cites W2031498112 @default.
- W2048493057 cites W2039723262 @default.
- W2048493057 cites W2044972799 @default.
- W2048493057 cites W2049831779 @default.
- W2048493057 cites W2052781489 @default.
- W2048493057 cites W2056385239 @default.
- W2048493057 cites W2060026323 @default.
- W2048493057 cites W2060779939 @default.
- W2048493057 cites W2061472949 @default.
- W2048493057 cites W2062519842 @default.
- W2048493057 cites W2063061748 @default.
- W2048493057 cites W2063160396 @default.
- W2048493057 cites W2063471837 @default.
- W2048493057 cites W2069898350 @default.
- W2048493057 cites W2072004541 @default.
- W2048493057 cites W2079456499 @default.
- W2048493057 cites W2080987263 @default.
- W2048493057 cites W2081698786 @default.
- W2048493057 cites W2083326922 @default.
- W2048493057 cites W2088327041 @default.
- W2048493057 cites W2089088411 @default.
- W2048493057 cites W2089270902 @default.
- W2048493057 cites W2091210609 @default.
- W2048493057 cites W2091458955 @default.
- W2048493057 cites W2092284266 @default.
- W2048493057 cites W2093160073 @default.
- W2048493057 cites W2093820551 @default.
- W2048493057 cites W2095659067 @default.
- W2048493057 cites W2107227847 @default.
- W2048493057 cites W2111091274 @default.
- W2048493057 cites W2111511922 @default.
- W2048493057 cites W2134776666 @default.
- W2048493057 cites W2137625625 @default.
- W2048493057 cites W2152128412 @default.
- W2048493057 cites W2152138626 @default.
- W2048493057 cites W2165916941 @default.
- W2048493057 cites W2175848502 @default.
- W2048493057 cites W2334208199 @default.
- W2048493057 cites W2416603275 @default.
- W2048493057 cites W2489427143 @default.
- W2048493057 cites W2950769127 @default.
- W2048493057 cites W2952322792 @default.
- W2048493057 cites W3004763826 @default.
- W2048493057 cites W996197731 @default.
- W2048493057 doi "https://doi.org/10.1038/srep05938" @default.
- W2048493057 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4120373" @default.
- W2048493057 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25087485" @default.
- W2048493057 hasPublicationYear "2014" @default.
- W2048493057 type Work @default.
- W2048493057 sameAs 2048493057 @default.
- W2048493057 citedByCount "46" @default.
- W2048493057 countsByYear W20484930572015 @default.
- W2048493057 countsByYear W20484930572016 @default.
- W2048493057 countsByYear W20484930572017 @default.
- W2048493057 countsByYear W20484930572018 @default.